14(S)-Hydroxy Docosahexaenoic Acid

Product Name: 14(S)-Hydroxy Docosahexaenoic Acid
CAS No.: 119433-37-3
Chemical Name: 14(S)-Hydroxy Docosahexaenoic Acid
Synonyms: 14(S)-HDHA;14(S)-HDoHE;14(S) HDHA,14(S)HDHA;ZNEBXONKCYFJAF-OUKOMXQNSA-N;14(S)-Hydroxy Docosahexaenoic Acid;14(S)-hydroxy Docosahexaenoic Acid/14(S)-HDHA in Ethanol;14(S)-hydroxy-4(Z),7(Z),10(Z),12(E),16(Z),19(Z)-docosahexaenoic acid;4,7,10,12,16,19-Docosahexaenoic acid, 14-hydroxy-, (4Z,7Z,10Z,12E,14S,16Z,19Z)-
CBNumber: CB02694827
Molecular Formula: C22H32O3
Formula Weight: 344.49
MOL File: 119433-37-3.mol

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14(S)-Hydroxy Docosahexaenoic Acid Property

Boiling point:: 510.0±50.0 °C(Predicted)
Density: 0.995±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.5 mg/ml
pka: 4.58±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15253
Product name: 14(S)-HDHA
Purity: ≥98%
Packaging: 25μg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 15253
Product name: 14(S)-HDHA
Purity: ≥98%
Packaging: 50μg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 15253
Product name: 14(S)-HDHA
Purity: ≥98%
Packaging: 100μg
Price: $286
Updated: 2024/03/01

Cayman Chemical

Product number: 29142
Product name: 14(S)-HDHA MaxSpec® Standard
Packaging: 10μg
Price: $127
Updated: 2023/06/20

TRC

Product number: H939590
Product name: 14(S)-HydroxyDocosahexaenoicAcid
Packaging: 25μg
Price: $45
Updated: 2021/12/16

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14(S)-Hydroxy Docosahexaenoic Acid Chemical Properties,Usage,Production

Description

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA; ). It is a precursor to the pro-resolving mediator maresin 1 and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis.

Uses

Docosahexaenoic acid (DHA; ) is a nutritionally-derived ω-3 fatty acid that is abundant in the brain and the retina and is thought to be important in early development and for therapeutic approaches to inflammatory disorders and cancer. 14(S)-HDHA is an oxygenation product of DHA that serves as a precursor to maresin 1 , an anti-inflammatory, pro-resolving mediator that prevents polymorphonuclear neutrophil (PMN) infiltration and stimulates macrophage phagocytosis. At doses as low as 0.2 ng/mouse 14(S)-HDHA administration resulted in reduced infiltration of PMNs into sites of inflammation.[Cayman Chemical]

Uses

14(S)-Hydroxy Docosahexaenoic Acid is formed by human platelets. 14(S)-Hydroxy Docosahexaenoic Acid reacts with activated macrophages to form dihydroxy-containg products which posses potent antiinflammatory and proresolving activity.

Definition

ChEBI: (14S)-HDoHE is a 14-HDoHE in which the stereocentre at position 14 has S-configuration. It is a conjugate acid of a (14S)-HDoHE(1-). It is an enantiomer of a (14R)-HDoHE.

14(S)-Hydroxy Docosahexaenoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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119433-37-3, 14(S)-Hydroxy Docosahexaenoic AcidRelated Search:

14(S)-Hydroxy Docosahexaenoic Acid

14(S)-HDHA

ZNEBXONKCYFJAF-OUKOMXQNSA-N

4,7,10,12,16,19-Docosahexaenoic acid, 14-hydroxy-, (4Z,7Z,10Z,12E,14S,16Z,19Z)-

14(S)-hydroxy-4(Z),7(Z),10(Z),12(E),16(Z),19(Z)-docosahexaenoic acid

14(S) HDHA,14(S)HDHA

14(S)-HDoHE

14(S)-hydroxy Docosahexaenoic Acid/14(S)-HDHA in Ethanol

119433-37-3

Pharmaceuticals, Intermediates & Fine Chemicals