C12-Sphingosine

Product Name: C12-Sphingosine
CAS No.: 128427-86-1
Chemical Name: C12-Sphingosine
Synonyms: C12-Sphingosine;Sphingosine (d12:1);(2S,3R,E)-2-Aminododec-4-ene-1,3-diol;4-Dodecene-1,3-diol, 2-amino-, (2S,3R,4E)-
CBNumber: CB02708771
Molecular Formula: C12H25NO2
Formula Weight: 215.33
MOL File: 128427-86-1.mol

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C12-Sphingosine Property

Boiling point:: 364.8±42.0 °C(Predicted)
Density: 0.980±0.06 g/cm3(Predicted)
solubility: DMF: 10 mg/mL; DMSO: 2 mg/ml; Ethanol: miscible
form: A crystalline solid
pka: 11.83±0.45(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26893
Product name: Sphingosine (d12:1)
Packaging: 500μg
Price: $63
Updated: 2024/03/01

Cayman Chemical

Product number: 26893
Product name: Sphingosine (d12:1)
Packaging: 1mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 26893
Product name: Sphingosine (d12:1)
Purity: ≥95%
Packaging: 5mg
Price: $396
Updated: 2024/03/01

TRC

Product number: S680720
Product name: C12-Sphingosine
Packaging: 100mg
Price: $1540
Updated: 2021/12/16

AK Scientific

Product number: 8969CR
Product name: (2S,3R,4E)-2-Amino-4-dodecene-1,3-diol
Packaging: 1mg
Price: $461
Updated: 2021/12/16

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C12-Sphingosine Chemical Properties,Usage,Production

Description

Sphingosine (d12:1) is a short-chain sphingolipid. It decreases serine palmitoyltransferase activity in primary cultured mouse cerebellar cells in a concentration-dependent manner. Sphingosine (d12:1) (0.5-50 μM) decreases production of sphingosine (d18:1) , lactosylceramide (Item Nos. 27197 | 16983), galactosylceramide , and a variety of gangliosides in mouse cerebellar granule cells. [Matreya, LLC. Catalog No. 1838]

Uses

(2S,3R,4E)-2-Amino-4-dodecene-1,3-diol acts as a sphingolipid base that inhibits sphingosine kinase.

References

[1] E C MANDON. Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases.[J]. European journal of biochemistry, 1991, 198 3: 667-674. DOI: 10.1111/j.1432-1033.1991.tb16065.x
[2] G. ECHTEN. Modulation of sphingolipid biosynthesis in primary cultured neurons by long chain bases.[J]. The Journal of Biological Chemistry, 1990, 120 1: 9333-9339. DOI: 10.1016/s0021-9258(19)38853-2

C12-Sphingosine Preparation Products And Raw materials

Raw materials

Preparation Products

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C12-Sphingosine Suppliers

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128427-86-1, C12-SphingosineRelated Search:

C12-Sphingosine

Sphingosine (d12:1)

4-Dodecene-1,3-diol, 2-amino-, (2S,3R,4E)-

(2S,3R,E)-2-Aminododec-4-ene-1,3-diol

128427-86-1