ChemicalBook > CAS DataBase List > N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane

N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane

Product Name
N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane
CAS No.
1263166-93-3
Chemical Name
N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane
Synonyms
BCN-amine;BCN-POE3-NH2;BCN-PEG3-NH2;CAS_1263166-93-3;BCN-endo-PEG2-NH2;endo-BCN-PEG2-NH2;ndo-BCN-PEG2-amine;(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl?N-[2-[2-(2-aminoethoxy)ethoxy]ethyl…;N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane;N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane >
CBNumber
CB02708867
Molecular Formula
C17H28N2O4
Formula Weight
324.42
MOL File
1263166-93-3.mol
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N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane Property

Boiling point:
487.1±30.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
12.05±0.46(Predicted)
form 
clear liquid
color 
Light yellow to Yellow to Orange
InChI
InChI=1S/C17H28N2O4/c1-21-17(20)15(12-23-11-10-22-9-8-18)19-16-13-6-4-2-3-5-7-14(13)16/h13-16,19H,4-12,18H2,1H3
InChIKey
GJZGRRKLPANLGK-UHFFFAOYSA-N
SMILES
C(N)COCCOCC(C(OC)=O)NC1C2C1CCC#CCC2
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Safety

WGK Germany 
3
HS Code 
2924.29.9500
Storage Class
10 - Combustible liquids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
745073
Product name
N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
Purity
for Copper-free Click Chemistry
Packaging
25mg
Price
$225
Updated
2026/03/19
Sigma-Aldrich
Product number
745073
Product name
N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
Purity
for Copper-free Click Chemistry
Packaging
100mg
Price
$748
Updated
2026/03/19
TCI Chemical
Product number
B4062
Product name
N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane
Purity
>90.0%(HPLC)
Packaging
25mg
Price
$212
Updated
2026/03/19
TCI Chemical
Product number
B4062
Product name
N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane
Purity
>90.0%(HPLC)
Packaging
100mg
Price
$691
Updated
2026/03/19
TRC
Product number
B789413
Product name
N-(1R,8S,9S)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane
Packaging
2mg
Price
$60
Updated
2021/12/16
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N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane Chemical Properties,Usage,Production

Description

endo-BCN-PEG2-amine is a heterobifunctional PEG linker containing a BCN and an amine group. The BCN group can react with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Uses

Amine functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This strained cyclooctyne will react with azide functionalized compounds or biomolecules without the need for a copper catalyst to result in a stable triazole linkage.

reaction suitability

reaction type: click chemistry
reagent type: linker

IC 50

PEGs

N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane Suppliers

Americas 1 CHINA 55 Europe 1 India 1 Japan 1 United States 8 Global 67
Xi'an Kaixin Biotechnology Co., Ltd
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China
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View Lastest Price from N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
endo BCN-PEG2-amine 1263166-93-3
Price
US $0.00/mg
Min. Order
50mg
Purity
>95.00%
Supply Ability
250mg
Release date
2024-03-20

1263166-93-3, N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctaneRelated Search:

2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate

  • N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane
  • (1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate
  • BCN-amine
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  • BCN-endo-PEG2-NH2
  • <i>N</i>-(1<i>R</i>,8<i>S</i>,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane
  • BCN-POE3-NH2
  • N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane for Copper-free Click Chemistry
  • N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane &gt
  • BCN-PEG3-NH2
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  • <i>N</i>-[(1<i>R</i>,8<i>S</i>,9<i>s</i>)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane
  • (1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl?N-[2-[2-(2-aminoethoxy)ethoxy]ethyl…
  • 1263166-93-3
  • SiChem