AZD5423

Product Name: AZD5423
CAS No.: 1034148-04-3
Chemical Name: AZD5423
Synonyms: AZD5423;AZD 5423;AZD-5423;AZD5423, 10 mM in DMSO;AZD 5423,AZD5423,Inhibitor,Glucocorticoid Receptor,inhibit,AZD-5423;2,2,2-trifluoro-n-[(1r,2s)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]acetamide;2,2,2-Trifluoro-N-((1R,2S)-1-((1-(4-fluorophenyl)-1H-indazol-5-yl)oxy)-1-(3-methoxyphenyl)propan-2-yl)acetamide;Acetamide, 2,2,2-trifluoro-N-[(1S,2R)-2-[[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy]-2-(3-methoxyphenyl)-1-methylethyl]-
CBNumber: CB02714660
Molecular Formula: C25H21F4N3O3
Formula Weight: 487.45
MOL File: 1034148-04-3.mol

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AZD5423 Property

Boiling point:: 573.8±50.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (205.15 mM; Need ultrasonic)
pka: 10.39±0.46(Predicted)
form: Solid
color: White to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0027671
Product name: AZD5423
Purity: 99.85%
Packaging: 5mg
Price: $130
Updated: 2021/12/16

ChemScene

Product number: CS-0027671
Product name: AZD5423
Purity: 99.85%
Packaging: 10mg
Price: $220
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0018395
Product name: AZD-5423
Purity: 95.00%
Packaging: 5MG
Price: $505.71
Updated: 2021/12/16

ChemScene

Product number: CS-0027671
Product name: AZD5423
Purity: 99.85%
Packaging: 50mg
Price: $770
Updated: 2021/12/16

ChemScene

Product number: CS-0027671
Product name: AZD5423
Purity: 99.85%
Packaging: 100mg
Price: $1350
Updated: 2021/12/16

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AZD5423 Chemical Properties,Usage,Production

Uses

AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM)[1]. AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma[2].

References

[1] Werkstr?m V, et al. Safety, Pharmacokinetics and Pharmacodynamics of the Selective Glucocorticoid Receptor Modulator AZD5423 after Inhalation in Healthy Volunteers. Basic Clin Pharmacol Toxicol. 2016 Dec;119(6):574-581. DOI:10.1111/bcpt.12621
[2] Gauvreau GM, et al. A nonsteroidal glucocorticoid receptor agonist inhibits allergen-induced late asthmatic responses. Am J Respir Crit Care Med. 2015 Jan 15;191(2):161-7. DOI:10.1164/rccm.201404-0623OC

AZD5423 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZD5423 Suppliers

China 26 United States 7 Global 33

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1034148-04-3, AZD5423Related Search:

AZD5423

2,2,2-trifluoro-n-[(1r,2s)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]acetamide

AZD 5423;AZD-5423

Acetamide, 2,2,2-trifluoro-N-[(1S,2R)-2-[[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy]-2-(3-methoxyphenyl)-1-methylethyl]-

AZD 5423,AZD5423,Inhibitor,Glucocorticoid Receptor,inhibit,AZD-5423

2,2,2-Trifluoro-N-((1R,2S)-1-((1-(4-fluorophenyl)-1H-indazol-5-yl)oxy)-1-(3-methoxyphenyl)propan-2-yl)acetamide

AZD5423, 10 mM in DMSO

1034148-04-3

C25H21F4N3O3