ChemicalBook > CAS DataBase List > (alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile

(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile

Product Name
(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
CAS No.
1150310-15-8
Chemical Name
(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
Synonyms
Entacapone impurity H;-oxo-1-piperidinepropanenitrile;(2E)-3-(3,4-Dihydroxy-5-nitrophenyl;Entacapone Impurity 8（Entacapone EP Impurity H）;-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-βEntacapone Impurity 8（Entacapone EP Impurity A）;Entacapone Impurity 24(Entacapone EP Impurity H);(E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)acrylonitrile;(E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile;(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile
CBNumber
CB02717373
Molecular Formula
C15H15N3O5
Formula Weight
317.3
MOL File
1150310-15-8.mol
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(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile Property

Melting point:
207-208℃ (ethanol )
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D454135
Product name
(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile
Packaging
100mg
Price
$205
Updated
2021/12/16
TRC
Product number
D454135
Product name
(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile
Packaging
250mg
Price
$475
Updated
2021/12/16
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(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile Chemical Properties,Usage,Production

Uses

(αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.

(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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(alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile Suppliers

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1150310-15-8, (alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrileRelated Search:

(E/Z)-3-O-Methyl Entacapone Entacapone EP IMpurity I (E)-3-O-Methyl Entacapone Entacapone 3,5-DINITROCATECHOL TYRPHOSTIN AG 1290 3,4-Dihydroxy-5-Nitrobenzoic Acid (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide 3-Nitro-4,5-dihydroxybenzaldehyde Entacapone EP Impurity G Entacapone EP IMpurity B Entacapone Impurity 10 Entacapone Impurity 4 6-Methoxy-2,4-dinitrophenol Entacapone 3-b-D-Glucuronide Entacapone Impurity 13 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N,N-diethyl-, (2E)- Entacapone EP IMpurity D

  • (alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
  • Entacapone impurity H
  • Entacapone Impurity 24(Entacapone EP Impurity H)
  • (E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)prop-2-enenitrile
  • Entacapone Impurity 8（Entacapone EP Impurity H）
  • (2E)-3-(3,4-Dihydroxy-5-nitrophenyl
  • 1-Piperidinepropanenitrile, α-[(3,4-dihydroxy-5-nitrophenyl)methylene]-β-oxo-, (αE)-
  • -[(3,4-Dihydroxy-5-nitrophenyl)methylene]-&beta
  • -oxo-1-piperidinepropanenitrile
  • Entacapone Impurity 8（Entacapone EP Impurity A）
  • (αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile
  • (E)-3-(3,4-Dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)acrylonitrile (Entacapone Impurity)
  • (E)-3-(3,4-dihydroxy-5-nitrophenyl)-2-(piperidine-1-carbonyl)acrylonitrile
  • 1150310-15-8