1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione
- Product Name
- 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione
- CAS No.
- 1197377-31-3
- Chemical Name
- 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione
- Synonyms
- 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidin...;2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione;1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione;1-(2-chloro-1-hydroxy-3-(quinolin-6-yl)propyl)pyrrolidine-2,5-dione;2,5-Pyrrolidinedione, 1-[2-chloro-1-hydroxy-3-(6-quinolinyl)propyl]-
- CBNumber
- CB02717676
- Molecular Formula
- C16H15ClN2O3
- Formula Weight
- 318.75
- MOL File
- 1197377-31-3.mol
1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione Property
- Boiling point:
- 598.3±50.0 °C(Predicted)
- Density
- 1.434±0.06 g/cm3(Predicted)
- vapor pressure
- 0-0Pa at 20-25℃
- pka
- 11.45±0.20(Predicted)
- InChI
- InChI=1S/C16H15ClN2O3/c17-12(16(22)19-14(20)5-6-15(19)21)9-10-3-4-13-11(8-10)2-1-7-18-13/h1-4,7-8,12,16,22H,5-6,9H2
- InChIKey
- FUPWOFWDARMISK-UHFFFAOYSA-N
- SMILES
- N1(C(O)C(Cl)CC2=CC=C3C(=C2)C=CC=N3)C(=O)CCC1=O
- LogP
- 0.9 at 20℃ and pH7
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione Chemical Properties,Usage,Production
Synthesis
A solution of 3-quinolin-6-ylpropanal in acetonitrile was cooled to 0° C before L-proline, benzoic acid, and N-chlorosuccinimide were added at 0° C. The reaction mixture was stirred at 0° C for 3 h, and the resulting clear solution was allowed to warm to room temperature and stirred at RT for 18 h. The reaction mixture became a thick suspension, and LCMS showed the completion of the reaction. Ethyl acetate (EtOAc) was added to the reaction mixture, stirring at room temperature for 1 h. The solids were collected by filtration, washed with ethyl acetate, and dried under vacuum at 40-45° C to constant weight to afford 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione as an off-white powder. yield: 65.
1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione Preparation Products And Raw materials
Raw materials
Preparation Products
1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione Suppliers
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View Lastest Price from 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione manufacturers
- Product
- 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione 1197377-31-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-21
- Product
- 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione 1197377-31-3
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- 1-[2-Chloro-1-hydroxy-3-(6-quinolinyl)propyl]-2,5-pyrrolidinedione 1197377-31-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- ≥98% by HPLC
- Supply Ability
- 100kg/month
- Release date
- 2023-07-22