ChemicalBook > CAS DataBase List > Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

Product Name
Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
CAS No.
168958-19-8
Chemical Name
Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
Synonyms
Peramivir Impurity 37;(1R,4R)-methyl 4-(tert-butoxycarbonylamino)cyclopent-2-enecarboxylate;Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester;2-Cyclopentene-1-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,4R)-
CBNumber
CB02729183
Molecular Formula
C12H19NO4
Formula Weight
241.28
MOL File
168958-19-8.mol
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Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Property

Boiling point:
331.2±42.0 °C(Predicted)
Density 
1.10±0.1 g/cm3(Predicted)
solubility 
soluble in Methanol
pka
11.75±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D474245
Product name
(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylicAcidMethylEster
Packaging
25mg
Price
$250
Updated
2021/12/16
TRC
Product number
D474245
Product name
(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylicAcidMethylEster
Packaging
50mg
Price
$445
Updated
2021/12/16
Abosyn
Product number
10-3382
Product name
(1R,4R)-methyl4-((tert-butoxycarbonyl)amino)cyclopent-2-enecarboxylate
Purity
95%-98%
Packaging
1g
Price
$400
Updated
2021/12/16
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Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Chemical Properties,Usage,Production

Uses

(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Suppliers

ChemStrong Scientific Co.,Ltd
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View Lastest Price from Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Peramivir Impurity 75 168958-19-8
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-25