ChemicalBook > CAS DataBase List > 5-Chloromethyl-2H-1,2,4-triazolin-3-one

5-Chloromethyl-2H-1,2,4-triazolin-3-one

Product Name
5-Chloromethyl-2H-1,2,4-triazolin-3-one
CAS No.
252742-72-6
Chemical Name
5-Chloromethyl-2H-1,2,4-triazolin-3-one
Synonyms
5-(chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one;3-Chloromethyl-1,2,4-triazol-5-one;3-Chloromethyl-1,2,4-triazolin-5-one;CjH4CIN3O;-5(4H)-one;Aprepitant Impurity 51;5-Chloromethyl-1H-[1,2,4]triazol-3-ol;5-(Chloromethyl)-4h-1,2,4-triazol-3-ol;5-ChloroMethyl-2H-1,2,4-triazolin-3-one
CBNumber
CB0273237
Molecular Formula
C3H4ClN3O
Formula Weight
133.54
MOL File
252742-72-6.mol
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5-Chloromethyl-2H-1,2,4-triazolin-3-one Property

Melting point:
199°C(lit.)
Density 
1.83±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
7.46±0.20(Predicted)
color 
White to Almost white
CAS DataBase Reference
252742-72-6
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Safety

RIDADR 
UN 3261 8/PG II
HazardClass 
8
PackingGroup 
II
HS Code 
2914390090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3094
Product name
3-(Chloromethyl)-1,2,4-triazolin-5-one
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$91
Updated
2024/03/01
TCI Chemical
Product number
C3094
Product name
3-(Chloromethyl)-1,2,4-triazolin-5-one
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$275
Updated
2024/03/01
TRC
Product number
C369885
Product name
5-Chloromethyl-2H-1,2,4-triazolin-3-one
Packaging
10mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
W4857
Product name
3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one
Packaging
250mg
Price
$72
Updated
2021/12/16
AK Scientific
Product number
W4857
Product name
3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one
Packaging
1g
Price
$78
Updated
2021/12/16
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5-Chloromethyl-2H-1,2,4-triazolin-3-one Chemical Properties,Usage,Production

Chemical Properties

White to Almost white powder to crystal

Uses

5-Chloromethyl-2H-1,2,4-triazolin-3-one is an intermediate used in the synthesis of Aprepitant (A729800) and Fosaprepitant, used as antiemetic drugs.

Application

3-Chloromethyl-1,2,4-triazolin-5-one is an intermediate in organic synthesis and pharmaceutical intermediate, which can be used in laboratory R&D synthesis process and chemical biological R&D process.

Hazard

5-Chloromethyl-2H-1,2,4-triazolin-3-one is a hazardous chemical that is corrosive to metals, irritating to the eyes and skin, and may cause respiratory irritation.

5-Chloromethyl-2H-1,2,4-triazolin-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloromethyl-2H-1,2,4-triazolin-3-one Suppliers

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View Lastest Price from 5-Chloromethyl-2H-1,2,4-triazolin-3-one manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
3-Chloromethyl-1,2,4-triazolin-5-one 252742-72-6
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-12-06
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
5-Chloromethyl-2H-1,2,4-triazolin-3-one 252742-72-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
5 MTs
Release date
2024-05-11
Hangzhou ICH Biofarm Co., Ltd
Product
3-Chloromethyl-1,2,4-triazolin-5-one 252742-72-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
≥1kg
Release date
2023-07-18

252742-72-6, 5-Chloromethyl-2H-1,2,4-triazolin-3-oneRelated Search:

Caprolactam Aprepitant Acetaminophen Rivaroxaban 5-Chloromethyl-2H-1,2,4-triazolin-3-one

  • 5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE
  • 3-Chloromethyl-1,2,4-triazol-5-one
  • 3-Chloromethyl-1,2,4-triazolin-5-one
  • 3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one
  • 3-(chloroMethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
  • 5-(CHLOORMETHYL)-1,2-DIHYDRO-3H-1,2,4-TRIAZOOL-3-ON
  • 5-Chloromethyl-2,4-Dithydro-[1,2,4]Triazol-3-One
  • Aprepitant Impurity 51
  • 5-Chloromethyl-1H-[1,2,4]triazol-3-ol
  • 5-ChloroMethyl-2H-1,2,4-triazolin-3-one
  • 3-Chloromethyl-1,2,4-triazolin-5-one,Aprepitant intermediate
  • 3-Chloromethyl-1,2,4-triazolin-5-one 5-Chloromethyl-2,4-dihydro-[1,2,4]triazol-3-one
  • Aprepitant int-2 3-chloromethyl-1,2,4-triazolin-5-one
  • 5-(chloromethyl)-1,2-dihydro-1,2,4-triazol-3-one
  • 5-(chloromethyl)-1,2-dihydro-3H-1,2,4-Triazol-3-one
  • (chloromethyl)-1,2-dihydro-1,2,4-triazol-3-one
  • -5(4H)-one
  • 3H-1,2,4-Triazol-3-one, 5-(chloromethyl)-1,2-dihydro-
  • 5-(Chloromethyl)-4h-1,2,4-triazol-3-ol
  • 5-(chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
  • Aprepitant intermediates，5-Chloromethyl-2,4-dihydro-〔1,2,4〕 triazol-3-one
  • 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione,6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-6-yl)-
  • CjH4CIN3O
  • 5-Chloromethyl-2,3-dihydro-4H-1,2,4-triazol-3-one
  • 252742-72-6
  • C3H4CIN3O
  • C3H4ClN3O
  • pharmacetical