ChemicalBook > CAS DataBase List > 5-Chloromethyl-2H-1,2,4-triazolin-3-one

5-Chloromethyl-2H-1,2,4-triazolin-3-one

Product Name
5-Chloromethyl-2H-1,2,4-triazolin-3-one
CAS No.
252742-72-6
Chemical Name
5-Chloromethyl-2H-1,2,4-triazolin-3-one
Synonyms
5-(chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one;3-Chloromethyl-1,2,4-triazol-5-one;3-Chloromethyl-1,2,4-triazolin-5-one;CjH4CIN3O;-5(4H)-one;Aprepitant Impurity 51;5-Chloromethyl-1H-[1,2,4]triazol-3-ol;5-(Chloromethyl)-4h-1,2,4-triazol-3-ol;5-ChloroMethyl-2H-1,2,4-triazolin-3-one
CBNumber
CB0273237
Molecular Formula
C3H4ClN3O
Formula Weight
133.54
MOL File
252742-72-6.mol
More
Less

5-Chloromethyl-2H-1,2,4-triazolin-3-one Property

Melting point:
199°C(lit.)
Density 
1.83±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
7.46±0.20(Predicted)
color 
White to Almost white
CAS DataBase Reference
252742-72-6
More
Less

Safety

RIDADR 
UN 3261 8/PG II
HazardClass 
8
PackingGroup 
II
HS Code 
2914390090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C3094
Product name
3-(Chloromethyl)-1,2,4-triazolin-5-one
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$91
Updated
2024/03/01
TCI Chemical
Product number
C3094
Product name
3-(Chloromethyl)-1,2,4-triazolin-5-one
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$275
Updated
2024/03/01
TRC
Product number
C369885
Product name
5-Chloromethyl-2H-1,2,4-triazolin-3-one
Packaging
10mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
W4857
Product name
3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one
Packaging
250mg
Price
$72
Updated
2021/12/16
AK Scientific
Product number
W4857
Product name
3-(Chloromethyl)-1H-1,2,4-triazol-5(4H)-one
Packaging
1g
Price
$78
Updated
2021/12/16
More
Less

5-Chloromethyl-2H-1,2,4-triazolin-3-one Chemical Properties,Usage,Production

Uses

5-Chloromethyl-2H-1,2,4-triazolin-3-one is an intermediate used in the synthesis of Aprepitant (A729800) and Fosaprepitant, used as antiemetic drugs.

Application

3-Chloromethyl-1,2,4-triazolin-5-one is an intermediate in organic synthesis and pharmaceutical intermediate, which can be used in laboratory R&D synthesis process and chemical biological R&D process.

Hazard

5-Chloromethyl-2H-1,2,4-triazolin-3-one is a hazardous chemical that is corrosive to metals, irritating to the eyes and skin, and may cause respiratory irritation.

5-Chloromethyl-2H-1,2,4-triazolin-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Chloromethyl-2H-1,2,4-triazolin-3-one Suppliers

Americas 1 Canada 1 China 249 India 10 Japan 2 United Kingdom 3 United States 16 Global 282
Alchemist-pharm chemical Technology Co. Ltd.
Tel
0371-67991738 13783628208
Fax
QQ 412703949
Email
carl@alchemist-pharm.com
Country
China
ProdList
43
Advantage
58
Viwit Pharmaceutical Co., Ltd.
Tel
0632-2980981 15063270987
Fax
0632-2989678
Email
service.china3@viwit.com
Country
China
ProdList
116
Advantage
55
Enantiotech Corporation Ltd
Tel
760-85282375 13212762451
Email
marketing@enantiotech.net
Country
China
ProdList
179
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18089
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
TaiZhou ZhiCheng Chemicals & Technology Co., LTD.
Tel
0523-82837785 13365232216
Fax
0523-87913272
Email
info@jszchg.com
Country
China
ProdList
245
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2893
Advantage
58
Shanghai SynFarm Pharmaceutical Technology Co., Ltd.
Tel
021-50793966 18917198199
Fax
+86-21-50793967
Email
info@synfarm.com
Country
China
ProdList
280
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Moltt Biocem Co., Ltd.
Tel
+86-21-38682181 15900741819
Fax
+86-21-38682181
Country
China
ProdList
282
Advantage
55
China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
ProdList
764
Advantage
50
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7876
Advantage
55
Shanghai YueChen International Trading Co. Ltd
Tel
021-67256163
Fax
021-67256081
Email
shanghailechen@163.com
Country
China
ProdList
171
Advantage
55
CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
Country
China
ProdList
1785
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6730
Advantage
55
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Hydragon Pharma Ltd
Tel
021-50215258
Fax
021-50215756
Email
market@hypharma.com
Country
China
ProdList
321
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Lihe Wuhan New Chemical Materials Co., Ltd.
Tel
027-88395709
Fax
027-88391805
Country
China
ProdList
430
Advantage
50
Shenzhen Nexconn Pharmatechs Ltd.
Tel
0755-89396905
Email
admin@nexconn.com
Country
China
ProdList
304
Advantage
55
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Guangzhou Ciming Biological Technology Co., Ltd.
Tel
020-38082199,29065168,38082986,29878298,29866629,4000192398
Fax
+86 (20)38082986
Country
China
ProdList
831
Advantage
60
Weifang QianJin Fine Chemical Co., Ltd.
Tel
0536-2457064 13031698386
Fax
0536-8897109
Email
1577399715@qq.COM
Country
China
ProdList
1691
Advantage
55
Atop Bio-Tech (Tianjin) Co., Ltd. (Atop)
Tel
022-66200236 18622210341
Fax
+86-022-66200236
Email
sales@atop-biotech.com
Country
China
ProdList
297
Advantage
60
Xishi Chemical (Shanghai) Co., Ltd.
Tel
021-60499358 13661956116
Fax
+86 (21) 5106-9359
Email
info@cs-pharm.com
Country
China
ProdList
186
Advantage
58
DebyeTec.com Inc.
Tel
18086626237 18086626237
Fax
qq:2693528373
Email
sales@debyesci.com
Country
China
ProdList
2643
Advantage
56
Wuhan Kai Lun new material Chemical Co Ltd
Tel
025-87787262
Fax
025-87787262
Country
China
ProdList
496
Advantage
58
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6508
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9254
Advantage
55
Chengdu Research Accelerators Technology Co., Ltd.
Tel
028-64353063
Fax
028-64353063 QQ:784253935
Email
reacchemical@163.com
Country
China
ProdList
5259
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5881
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Nanjing Gold Pharmaceutical Technology Co. Ltd.
Tel
025-84209270; 15905158493
Fax
025-84209270
Email
wgp@nanjing-pharmaceutical.com
Country
China
ProdList
69
Advantage
55
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
More
Less

View Lastest Price from 5-Chloromethyl-2H-1,2,4-triazolin-3-one manufacturers

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
5-Chloromethyl-2H-1,2,4-triazolin-3-one 252742-72-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
5 MTs
Release date
2024-05-11
Hangzhou ICH Biofarm Co., Ltd
Product
3-Chloromethyl-1,2,4-triazolin-5-one 252742-72-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
≥1kg
Release date
2023-07-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE 252742-72-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

252742-72-6, 5-Chloromethyl-2H-1,2,4-triazolin-3-oneRelated Search:

Caprolactam Aprepitant Acetaminophen Rivaroxaban 5-Chloromethyl-2H-1,2,4-triazolin-3-one

  • 5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE
  • 3-Chloromethyl-1,2,4-triazol-5-one
  • 3-Chloromethyl-1,2,4-triazolin-5-one
  • 3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one
  • 3-(chloroMethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one
  • 5-(CHLOORMETHYL)-1,2-DIHYDRO-3H-1,2,4-TRIAZOOL-3-ON
  • 5-Chloromethyl-2,4-Dithydro-[1,2,4]Triazol-3-One
  • Aprepitant Impurity 51
  • 5-Chloromethyl-1H-[1,2,4]triazol-3-ol
  • 5-ChloroMethyl-2H-1,2,4-triazolin-3-one
  • 3-Chloromethyl-1,2,4-triazolin-5-one,Aprepitant intermediate
  • 3-Chloromethyl-1,2,4-triazolin-5-one 5-Chloromethyl-2,4-dihydro-[1,2,4]triazol-3-one
  • Aprepitant int-2 3-chloromethyl-1,2,4-triazolin-5-one
  • 5-(chloromethyl)-1,2-dihydro-1,2,4-triazol-3-one
  • 5-(chloromethyl)-1,2-dihydro-3H-1,2,4-Triazol-3-one
  • (chloromethyl)-1,2-dihydro-1,2,4-triazol-3-one
  • -5(4H)-one
  • 3H-1,2,4-Triazol-3-one, 5-(chloromethyl)-1,2-dihydro-
  • 5-(Chloromethyl)-4h-1,2,4-triazol-3-ol
  • 5-(chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
  • Aprepitant intermediates，5-Chloromethyl-2,4-dihydro-〔1,2,4〕 triazol-3-one
  • 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione,6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-6-yl)-
  • CjH4CIN3O
  • 5-Chloromethyl-2,3-dihydro-4H-1,2,4-triazol-3-one
  • 252742-72-6
  • C3H4CIN3O
  • C3H4ClN3O
  • pharmacetical