(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one

Product Name: (3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one
CAS No.: 1251741-03-3
Chemical Name: (3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one
Synonyms: Ezetimibe Double Defluorinated;Ezetimibe Didesfluoro impurity;(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one;2-Azetidinone, 4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-1-phenyl-, (3R,4S)-;(3R,4S)-3-(3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one - [AC80815]
CBNumber: CB02735582
Molecular Formula: C24H23NO3
Formula Weight: 373.44
MOL File: 1251741-03-3.mol

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(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one Property

Boiling point:: 642.9±55.0 °C(Predicted)
Density: 1.251±0.06 g/cm3(Predicted)
pka: 9.72±0.30(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D476728
Product name: Di-desfluoroEzetimibe
Packaging: 2.5mg
Price: $100
Updated: 2021/12/16

TRC

Product number: D476728
Product name: Di-desfluoroEzetimibe
Packaging: 5mg
Price: $195
Updated: 2021/12/16

TRC

Product number: D476728
Product name: Di-desfluoroEzetimibe
Packaging: 10mg
Price: $365
Updated: 2021/12/16

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(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one Chemical Properties,Usage,Production

Uses

Di-desfluoro Ezetimibe is a dehalogenated impurities observed in halogen-containing pharmaceuticals. Also, it is a related compound to Ezetimibe (E975000), which is an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one Suppliers

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1251741-03-3, (3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-oneRelated Search:

NA Ezetimibe Impurity 70 Ezetimibe Impurity 50 (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide Ezetimibe Impurity 11 (S)-3-((2R,5R)-5-(4-fluorophenyl)-2-((S)-(4-fluorophenylaMino)(4-hydroxyphenyl)Methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one Ezetimibe Impurity (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-(4-fluorophenylaMino)(4-hydroxyphenyl)Methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one Ezetimibe Impurity 43 4-[[(4-Fluorophenyl)imino]methyl]-phenol (S)-3-((2R,5R)-5-(4-fluorophenyl)-5-hydroxy-2-((S)-hydroxy(4-hydroxyphenyl)methyl)pentanoyl)-4-phenyloxazolidin-2-one (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one EzetiMibe Dehydoxy IMpurity (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone Ezetimibe Impurity 36 Ezetimibe Impurity 35 EzetiMibe ring-opening dehydrate iMpurity (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one

Ezetimibe Didesfluoro impurity

Ezetimibe Double Defluorinated

2-Azetidinone, 4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-phenylpropyl]-1-phenyl-, (3R,4S)-

(3R,4S)-3-(3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one - [AC80815]

1251741-03-3