3,6-Dibromo-fluoren-9-one
- Product Name
- 3,6-Dibromo-fluoren-9-one
- CAS No.
- 216312-73-1
- Chemical Name
- 3,6-Dibromo-fluoren-9-one
- Synonyms
- NSC 86559;6-Dibromo-fluoren-9-one;3,6-Dibromo-9-fluorenone;3,6-Dibromofluorene-9-one;3,6-Dibromo-fluoren-9-one;3,6-Dibromo-9H-fluoren-9-on;3,6-dibromo-9H-fluoren-9-one;3,6-Dibromo-9H-fluorene-9-one;9H-FLUOREN-9-ONE, 3,6-DIBROMO-
- CBNumber
- CB02737142
- Molecular Formula
- C13H6Br2O
- Formula Weight
- 337.99
- MOL File
- 216312-73-1.mol
3,6-Dibromo-fluoren-9-one Property
- Melting point:
- 321 °C
- Boiling point:
- 448.5±38.0 °C(Predicted)
- Density
- 1.907±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Very Slightly), DMSO (Very Slightly, Heated)
- form
- Solid
- color
- Yellow
- InChI
- InChI=1S/C13H6Br2O/c14-7-1-3-9-11(5-7)12-6-8(15)2-4-10(12)13(9)16/h1-6H
- InChIKey
- XXZOHYHKWDLSFS-UHFFFAOYSA-N
- SMILES
- C1(=O)C2=C(C=C(Br)C=C2)C2=C1C=CC(Br)=C2
- CAS DataBase Reference
- 216312-73-1
Safety
- HS Code
- 2914790090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- D5301
- Product name
- 3,6-Dibromo-9H-fluoren-9-one
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $103
- Updated
- 2026/03/19
- Product number
- D424682
- Product name
- 3,6-Dibromo-9H-fluoren-9-one
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- D424682
- Product name
- 3,6-Dibromo-9H-fluoren-9-one
- Packaging
- 1g
- Price
- $85
- Updated
- 2021/12/16
- Product number
- A157347
- Product name
- 3,6-Dibromo-9H-fluoren-9-one
- Purity
- 97%
- Packaging
- 250mg
- Price
- $9
- Updated
- 2021/12/16
- Product number
- A157347
- Product name
- 3,6-Dibromo-9H-fluoren-9-one
- Purity
- 97%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
3,6-Dibromo-fluoren-9-one Chemical Properties,Usage,Production
Uses
3,6-Dibromo-9H-fluoren-9-one is a reagent in the preparation of diphenylamine-fluorenone derivatives as potential fluorescent probes for neuroblastoma cell staining.
Synthesis
53348-05-3
216312-73-1
General procedure for the synthesis of 3,6-dibromo-9,10-phenanthrenequinone from 3,6-dibromo-9H-fluoren-9-one: 60.0 g (1.0 mol) of potassium hydroxide was dissolved in 400 ml of water, followed by the addition of 13.0 g (35.0 mmol) of 3,6-dibromoquinolinone obtained from step 1 to a 1000 ml three-necked flask. The reaction mixture was heated to 100 °C and kept at this temperature for 3 hours. During the reaction, 30.0 g (200.0 mmol) of potassium permanganate was added in batches and the reaction was continued for 10 hours after addition. Upon completion of the reaction, the mixture was cooled to room temperature. Subsequently, solid sodium thiosulfate powder was added to the reaction solution and the pH was adjusted to neutral, at which point a black solid precipitated. The precipitate was collected by filtration and the filter cake was wrapped in filter paper and placed in a Soxhlet extractor and extracted with dichloromethane for 3 consecutive days. After the extraction was completed, the dichloromethane solution was rotary evaporated to dryness to give 4.8 g of a light yellow solid, i.e., the intermediate 3,6-dibromo-9H-fluoren-9-one, in 40% yield.
References
[1] Journal of Materials Chemistry, 2012, vol. 22, # 10, p. 4383 - 4390
[2] Journal of Organic Chemistry, 2009, vol. 74, # 21, p. 8484 - 8487
[3] Tetrahedron Letters, 2010, vol. 51, # 37, p. 4894 - 4897
[4] Organic Letters, 2014, vol. 16, # 3, p. 936 - 939
[5] Journal of the American Chemical Society, 2004, vol. 126, # 19, p. 6035 - 6042
3,6-Dibromo-fluoren-9-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,6-Dibromo-fluoren-9-one manufacturers
- Product
- 3,6-Dibromo-fluoren-9-one 216312-73-1
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08
- Product
- 3,6-Dibromo-fluoren-9-one 216312-73-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95--99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08