1-Boc-4-amino-4-piperidineacetic acid
- Product Name
- 1-Boc-4-amino-4-piperidineacetic acid
- CAS No.
- 1159983-30-8
- Chemical Name
- 1-Boc-4-amino-4-piperidineacetic acid
- Synonyms
- 2-(4-Amino-1-(tert-butoxycarbonyl);1-Boc-4-amino-4-piperidineacetic acid;2-(1-Boc-4-amino-4-piperidyl)acetic Acid;2-(4-Amino-1-boc-piperidin-4-yl)acetic Acid;2-(4-AMINO-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)ACETIC ACID;4-Amino-1-[(1,1-dimethylethoxy)carbonyl]-4-piperidineacetic acid;4-Piperidineacetic acid, 4-amino-1-[(1,1-dimethylethoxy)carbonyl]-;2-[4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid
- CBNumber
- CB0274067
- Molecular Formula
- C12H22N2O4
- Formula Weight
- 258.31
- MOL File
- Mol file
1-Boc-4-amino-4-piperidineacetic acid Property
- Boiling point:
- 398.9±27.0 °C(Predicted)
- Density
- 1.158±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 4.66±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A602008
- Product name
- 2-(4-Amino-1-boc-piperidin-4-yl)aceticAcid
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- Y3168
- Product name
- 2-(4-Amino-1-(tert-butoxycarbonyl)piperidin-4-yl)aceticacid
- Packaging
- 250mg
- Price
- $201
- Updated
- 2021/12/16
- Product number
- CHM0377725
- Product name
- 2-(4-AMINO-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)ACETIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.79
- Updated
- 2021/12/16
- Product number
- A167462
- Product name
- 2-(4-Amino-1-(tert-butoxycarbonyl)piperidin-4-yl)aceticacid
- Purity
- 95%
- Packaging
- 5g
- Price
- $519
- Updated
- 2021/12/16
- Product number
- CM130768
- Product name
- 2-(4-amino-1-(tert-butoxycarbonyl)piperidin-4-yl)aceticacid
- Purity
- 95%
- Packaging
- 5g
- Price
- $785
- Updated
- 2021/12/16
1-Boc-4-amino-4-piperidineacetic acid Chemical Properties,Usage,Production
Uses
1-Boc-4-amino-4-piperidineacetic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
A mixture of 4-oxo-piperidine- 1 -carboxylic acid tert-butyl ester (3.5 g, 17.55 mmol) (Sigma- Aldrich), malonic acid (2.0 g, 19.30 mmol) and ammonium acetate (3.1 g, 40.36 mmol) in n-BuOH was refluxed for 3 h. After cooled, white solid was collected, rinsed with EtOAc and dried in vacuo to provide the title compound 1.61 g (6.2 mmol) in 36% yield.