Neopinone Property

Melting point:

118-130 °C

Boiling point:

470.0±45.0 °C(Predicted)

Density 

1.34±0.1 g/cm3(Predicted)

solubility 

soluble in Acetone

pka

7.94±0.20(Predicted)

Hazard and Precautionary Statements (GHS)

Neopinone Chemical Properties,Usage,Production

Uses

(5a)-8,14-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-oneNeopinon is an intermediate in synthesizing 7,8-Bis Hydromorphone (B443785). It is a derivative of hydromorphone. Hydromorphone is an opioid agonist, which is used for sedation, analgesia, and as a restraining agent.

Definition

ChEBI: Neopinone is the beta,gamma-unsaturated ketone resulting from the hydrolysis of the methyl enol ether group of thebaine. It is a key intermediate in the biosynthesis of codeine and morphine in the opium poppy, Papaver somniferum. It is a morphinane alkaloid and an organic heteropentacyclic compound. It is a conjugate base of a neopinone(1+). It derives from a hydride of a morphinan.