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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2

Product Name
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
CAS No.
689284-12-6
Chemical Name
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
Synonyms
TAPI-2 acetate salt;Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2;N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-
CBNumber
CB02750664
Molecular Formula
C19H37N5O5
Formula Weight
415.53
MOL File
689284-12-6.mol
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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Property

storage temp. 
-20°C
form 
lyophilized solid
color 
white to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0420
Product name
TAPI-2 acetate salt
Purity
≥98% (HPLC)
Packaging
1mg
Price
$380
Updated
2024/03/01
TRC
Product number
T731805
Product name
TAPI2
Packaging
1mg
Price
$265
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000229
Product name
TAPI-2
Purity
95.00%
Packaging
1MG
Price
$466.2
Updated
2021/12/16
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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Chemical Properties,Usage,Production

Uses

TAPI 2 is a matrix metalloprotease (MMP) inhibitor, which inhibits merpin α and β homo-oligomers.

Biochem/physiol Actions

TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001.

storage

Store at -20°C

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Suppliers

Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
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7892
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Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8618
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58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4031
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58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.com
Country
China
ProdList
24246
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58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
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58

689284-12-6, Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2Related Search:


  • N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide
  • TAPI-2 acetate salt
  • Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
  • N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide
  • L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-
  • 689284-12-6