ChemicalBook > CAS DataBase List > Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
- Product Name
- Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
- CAS No.
- 689284-12-6
- Chemical Name
- Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
- Synonyms
- TAPI-2 acetate salt;Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2;N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-
- CBNumber
- CB02750664
- Molecular Formula
- C19H37N5O5
- Formula Weight
- 415.53
- MOL File
- 689284-12-6.mol
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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Property
- storage temp.
- -20°C
- form
- lyophilized solid
- color
- white to off-white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0420
- Product name
- TAPI-2 acetate salt
- Purity
- ≥98% (HPLC)
- Packaging
- 1mg
- Price
- $380
- Updated
- 2024/03/01
TRC
- Product number
- T731805
- Product name
- TAPI2
- Packaging
- 1mg
- Price
- $265
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0000229
- Product name
- TAPI-2
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $466.2
- Updated
- 2021/12/16
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Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Chemical Properties,Usage,Production
Uses
TAPI 2 is a matrix metalloprotease (MMP) inhibitor, which inhibits merpin α and β homo-oligomers.
Biochem/physiol Actions
TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001.
storage
Store at -20°C
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Preparation Products And Raw materials
Raw materials
Preparation Products
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