5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide
- Product Name
- 5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide
- CAS No.
- 215778-97-5
- Chemical Name
- 5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide
- Synonyms
- CCCI-01;CCCI-01 >=98% (HPLC);5-nitro-N-(3-pyridinylmethyl)-2-furamide;Centrosome Clustering Chemical Inhibitor-01;5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide;5-Nitro-N-(pyridin-3-ylmethyl)furan-2-carboxamide;2-Furancarboxamide, 5-nitro-N-(3-pyridinylmethyl)-
- CBNumber
- CB02751090
- Molecular Formula
- C11H9N3O4
- Formula Weight
- 247.21
- MOL File
- 215778-97-5.mol
5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide Property
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- color
- white to beige
- InChI
- 1S/C11H9N3O4/c15-11(9-3-4-10(18-9)14(16)17)13-7-8-2-1-5-12-6-8/h1-6H,7H2,(H,13,15)
- InChIKey
- OBZHOVWNZIVCCZ-UHFFFAOYSA-N
- SMILES
- [N+](=O)([O-])c1[o]c(cc1)C(=O)NCc2cnccc2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML0988
- Product name
- CCCI-01
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $111
- Updated
- 2026/03/19
- Product number
- SML0988
- Product name
- CCCI-01
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $424
- Updated
- 2022/05/15
5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide Chemical Properties,Usage,Production
Uses
CCCI-01 is a centrosome clustering inhibitor. CCCI-01 has selective effects on cancer. CCCI-01 can be used for the research of non-cross-resistant anti-cancer agents with blocking centrosome clustering[1].
Biological Activity
CCCI-01 induces the fomation of multipolar spindles in cancer cells containing multiple, or supernumerary centromeres. CCCI-01 leads to centromere declustering, disruption of cell cycle and apoptsis in BT-549 breast cancer cells without affecting bipolar spindles in normal primary human mammary epithelial cells.
References
[1] Kawamura E, et al. Identification of novel small molecule inhibitors of centrosome clustering in cancer cells. Oncotarget. 2013 Oct;4(10):1763-76. DOI:10.18632/oncotarget.1198
5-Nitro-N-(3-pyridinylmethyl)-2-furancarboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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