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Ethyl (hydroxyimino)cyanoacetate potassium salt

Product Name
Ethyl (hydroxyimino)cyanoacetate potassium salt
CAS No.
158014-03-0
Chemical Name
Ethyl (hydroxyimino)cyanoacetate potassium salt
Synonyms
K-Oxyma;K-Oxyma 97%;K-Oxyma Pure;K-OXYMA PURE 25 G;K-Oxyma≥ 99% (HPLC);Potassium Oxyma Pure;OxymaPurepotassiumsalt;K-Oxyma Pure Novabiochem;Potassium2-cyano-2-(hydroxyimino)acetate;Ethyl (hydroxyimino)cyanoacetate potassium
CBNumber
CB02755629
Molecular Formula
C5H5KN2O3
Formula Weight
180.2031
MOL File
158014-03-0.mol
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Ethyl (hydroxyimino)cyanoacetate potassium salt Property

Melting point:
145-155°C
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Sparingly)
form 
Solid
color 
Dark Yellow
InChI
InChI=1S/C5H6N2O3.K/c1-2-10-5(8)4(3-6)7-9;/h9H,2H2,1H3;/q;+1/p-1/b7-4+;
InChIKey
ZFBMUWGNRJITLS-KQGICBIGSA-M
SMILES
[K+].C(OCC)(=O)/C(=N/[O-])/C#N
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Safety

Hazard Codes 
T
Risk Statements 
20/21-25-43
Safety Statements 
36/37-45
RIDADR 
UN 3439 6.1 / PGIII
WGK Germany 
3
HS Code 
2928 00 90
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51212
Product name
K-Oxyma Pure
Purity
Novabiochem?
Packaging
25g
Price
$45.7
Updated
2025/07/31
Sigma-Aldrich
Product number
8.51212
Product name
K-Oxyma Pure
Purity
Novabiochem?
Packaging
100g
Price
$119
Updated
2025/07/31
Sigma-Aldrich
Product number
776874
Product name
K-Oxyma
Purity
97%
Packaging
50g
Price
$186
Updated
2025/07/31
Sigma-Aldrich
Product number
776874
Product name
K-Oxyma
Purity
97%
Packaging
250g
Price
$677
Updated
2025/07/31
TRC
Product number
E937850
Product name
EthylCyanoglyxylate-2-oxymePotassiumSalt
Packaging
5g
Price
$50
Updated
2021/12/16
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Ethyl (hydroxyimino)cyanoacetate potassium salt Chemical Properties,Usage,Production

Chemical Properties

Bright yellow powder

Uses

Useful in peptide coupling on mild acid-labile resins with minimal to no cleavage of the peptide from the resin due to its more alkaline character. This can be used to replace the explosive HOBt and HOAt.

Uses

  • Non-explosive replacement for HOBt and HOAt with at least comparable performance to HOAt
  • Outperforms HOAt in sterically demanding peptide bond formations
  • Compatible with carbodiimide-mediated; solution and solid phase peptide coupling;
  • Less epimerization than HOBt in fragment condensation reactions
  • K-salt especially useful in peptide coupling on mild acid-labile resins such as 2-chlorotrityl; leading to minimal to no cleavage of the peptide from the resin due to its more alkaline character
  • K-salt has a higher melting point than OxymaPure

Uses

Ethyl (hydroxyimino)cyanoacetate potassium salt is a Non-explosive replacement for HOBt and HOAt with at least comparable performance to HOAt Outperforms HOAt in sterically demanding peptide bond formations Compatible with carbodiimide-mediated; solution and solid phase peptide coupling; Less epimerization than HOBt in fragment condensation reactions K-salt especially useful in peptide coupling on mild acid-labile resins such as 2-chlorotrityl; leading to minimal to no cleavage of the peptide from the resin due to its more alkaline character K-salt has a higher melting point than OxymaPure.

reaction suitability

reaction type: Coupling Reactions

Ethyl (hydroxyimino)cyanoacetate potassium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ethyl (hydroxyimino)cyanoacetate potassium salt manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl (hydroxyimino)cyanoacetate potassium salt 158014-03-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-23

158014-03-0, Ethyl (hydroxyimino)cyanoacetate potassium saltRelated Search:


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