ChemicalBook > CAS DataBase List > N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide
N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide
- Product Name
- N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide
- CAS No.
- 451491-47-7
- Chemical Name
- N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide
- Synonyms
- CTB >=98% (HPLC);Histone Acetyltransferase Activator, CTB;N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide;Benzamide, N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-;Histone Acetyltransferase Activator, CTB - CAS 451491-47-7 - Calbiochem;HATs,Inhibitor,neurons,CTB,Apoptosis,MCF-7 cell,cancer,potent,HAT,autophagic flux,inhibit,Histone Acetyltransferase
- CBNumber
- CB02755861
- Molecular Formula
- C16H13ClF3NO2
- Formula Weight
- 343.73
- MOL File
- 451491-47-7.mol
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N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide Property
- storage temp.
- 2-8°C
- solubility
- DMSO: >10mg/mL
- form
- powder
- color
- white to off-white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C6499
- Product name
- CTB
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $84.1
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 382120
- Product name
- Histone Acetyltransferase Activator, CTB
- Packaging
- 25mg
- Price
- $280
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C6499
- Product name
- CTB
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $226
- Updated
- 2024/03/01
American Custom Chemicals Corporation
- Product number
- CHM0151719
- Product name
- CTB
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.84
- Updated
- 2021/12/16
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N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide Chemical Properties,Usage,Production
Uses
CTB has been used to study its apoptotic effects on P53 protein acetylation.
Definition
ChEBI: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxybenzamide is a member of benzamides.
Biological Activity
CTPB was a first known small molecular activator of histone acetyltransferase p300. CTB is a simplified analog of CTPB with comparable or higher activity. The compound activates the histone acetyltransferase (HAT) activity of p300/EP300/E1A binding protein.', 'Small molecule activators of H at such as CTB (N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide) is useful for altering chromatin acetylation directly. It might serve as a therapeutic agent for treating the complications of cognitive dysfunction including neuropsychiatric, neurodevelopmental and neurodegenerative diseases.
N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
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