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Diminutol

Product Name
Diminutol
CAS No.
361431-33-6
Chemical Name
Diminutol
Synonyms
NG72;Diminutol;1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
CBNumber
CB02756303
Molecular Formula
C19H26N6OS
Formula Weight
386.51
MOL File
361431-33-6.mol
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Diminutol Property

storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18237
Product name
Diminutol
Purity
≥98%
Packaging
500μg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
18237
Product name
Diminutol
Purity
≥98%
Packaging
1mg
Price
$92
Updated
2024/03/01
Cayman Chemical
Product number
18237
Product name
Diminutol
Purity
≥98%
Packaging
5mg
Price
$380
Updated
2024/03/01
Cayman Chemical
Product number
18237
Product name
Diminutol
Purity
≥98%
Packaging
10mg
Price
$665
Updated
2024/03/01
Usbiological
Product number
447266
Product name
Diminutol
Packaging
5mg
Price
$651
Updated
2021/12/16
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Diminutol Chemical Properties,Usage,Production

Description

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.

Uses

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.[Cayman Chemical]

Uses

Diminutol is a cell-permeable purine analog that inhibits NQ01 and blocks mitotic spindle assembly.

Diminutol Preparation Products And Raw materials

Raw materials

Preparation Products

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Diminutol Suppliers

Shanghai Hongye Biotechnology Co. Ltd
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361431-33-6, DiminutolRelated Search:


  • Diminutol
  • NG72
  • 1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
  • 361431-33-6