4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE

Product Name: 4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE
CAS No.: 5432-53-1
Chemical Name: 4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE
Synonyms: 6(5H)-Phenanthridinone,3,10-dibromo-;4-(4-(Dimethylamino)phenyl)buten-2-one;1-(4-DIMETHYLAMINOPHENYL)BUT-1-EN-3-ONE;4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE;3-Buten-2-one, 4-[4-(dimethylamino)phenyl]-;4-(4-N,N-Dimethylaminophenyl)but-3-en-2-one
CBNumber: CB0276612
Molecular Formula: C12H15NO
Formula Weight: 189.25
MOL File: 5432-53-1.mol

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4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE Property

Melting point:: 234-235 °C
Boiling point:: 340.6±25.0 °C(Predicted)
Density: 1.039±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 4.88±0.24(Predicted)
Appearance: Light yellow to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D494133
Product name: 4-(4-(Dimethylamino)phenyl)but-3-en-2-one
Packaging: 500mg
Price: $175
Updated: 2021/12/16

AK Scientific

Product number: 7824AB
Product name: 4-(4-(Dimethylamino)phenyl)but-3-en-2-one
Packaging: 1g
Price: $183
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0025145
Product name: 4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE
Purity: 95.00%
Packaging: 50MG
Price: $727.65
Updated: 2021/12/16

Alichem

Product number: 5432531
Product name: 4-(4-(Dimethylamino)phenyl)but-3-en-2-one
Packaging: 1g
Price: $183
Updated: 2021/12/16

Chemenu

Product number: CM193850
Product name: (E)-4-(4-(dimethylamino)phenyl)but-3-en-2-one
Purity: 95+%
Packaging: 1g
Price: $187
Updated: 2021/12/16

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4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE Chemical Properties,Usage,Production

Synthesis

100-10-7

67-64-1

5432-53-1

GENERAL METHOD: p-Dimethylaminobenzaldehyde (50 mmol) was dissolved in acetone (50 mL) and the solution was cooled to 0°C in an ice bath. A 10% aqueous NaOH solution was slowly added dropwise to the reaction mixture, followed by a natural warming of the reaction system to room temperature. The reaction mixture was stirred continuously at room temperature until the reaction was complete. After completion of the reaction, the acetone was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate and washed twice each with dilute hydrochloric acid and water sequentially. The organic layer was separated and dried over anhydrous Na2SO4, followed by concentration under reduced pressure to remove the solvent. The crude product was purified by column chromatography (silica gel, 100-200 mesh, eluent ratio 9:1 hexane/ethyl acetate) to afford the target compound 4-(4-dimethylaminophenyl)-but-3-en-2-one.

References

[1] Journal of Medicinal Chemistry, 1992, vol. 35, # 19, p. 3429 - 3447
[2] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2010, vol. 49, # 7, p. 944 - 947
[3] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 12, p. 3784 - 3787
[4] Journal of Organic Chemistry, 1939, vol. 3, p. 13
[5] Helvetica Chimica Acta, 1931, vol. 14, p. 1340,1348

4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE Suppliers

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5432-53-1, 4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONERelated Search:

3,3'-CARBONYLBIS(7-DIETHYLAMINOCOUMARIN) Coumarin 334 7-DIETHYLAMINO-3-THENOYLCOUMARIN 4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE 4-(DIMETHYLAMINO)-4'-FLUOROCHALCONE 4-DIMETHYLAMINO-4'-METHYLCHALCONE 4-(DIMETHYLAMINO)CHALCONE 1,5-BIS(4-DIMETHYLAMINOPHENYL)-1,4-PENTADIEN-3-ONE 6-((E)-[4-(DIMETHYLAMINO)PHENYL]METHYLIDENE)-6,7,8,9-TETRAHYDRO-5H-BENZO[A]CYCLOHEPTEN-5-ONE 3-[4-(DIMETHYLAMINO)PHENYL]-1-(2-THIENYL)PROP-2-EN-1-ONE 1-(4-CHLOROPHENYL)-3-[4-(DIMETHYLAMINO)PHENYL]PROP-2-EN-1-ONE 2,6-BIS-(4-DIMETHYLAMINO-BENZYLIDENE)-CYCLOHEXANONE 3-[2-CHLORO-4-(DIMETHYLAMINO)PHENYL]-1-(4-CHLOROPHENYL)-2-PROPEN-1-ONE 1-[2-(BENZYLOXY)PHENYL]-3-[4-(1,1,1-TRIMETHYLAMMONIO)PHENYL]PROP-2-EN-1-ONE IODIDE 3-[4-(DIMETHYLAMINO)PHENYL]-1-(2-HYDROXYPHENYL)PROP-2-EN-1-ONE 3-ACETYL-7-(DIETHYLAMINO)-2H-CHROMEN-2-ONE 3-[4-(DIMETHYLAMINO)PHENYL]-1-(2-NITROPHENYL)PROP-2-EN-1-ONE 1-[2-(BENZYLOXY)PHENYL]-3-[4-(DIMETHYLAMINO)PHENYL]PROP-2-EN-1-ONE

4-(4-DIMETHYLAMINO-PHENYL)-BUT-3-EN-2-ONE

4-(4-N,N-Dimethylaminophenyl)but-3-en-2-one

1-(4-DIMETHYLAMINOPHENYL)BUT-1-EN-3-ONE

3-Buten-2-one, 4-[4-(dimethylamino)phenyl]-

4-(4-(Dimethylamino)phenyl)buten-2-one

6(5H)-Phenanthridinone,3,10-dibromo-

5432-53-1