ChemicalBook > CAS DataBase List > Hs 27
Hs 27
- Product Name
- Hs 27
- CAS No.
- 1562024-11-6
- Chemical Name
- Hs 27
- Synonyms
- Hs 27;HS27,HS 27;1562024-11-7;HS27;HS-27;HS 27;2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thio,HS-27;2-((1-((3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide;2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide,HS-27;2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27;Benzamide, 2-[[21-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-21-thioxo-4,7,10,13,16-pentaoxa-20-azaheneicos-1-yl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indazol-1-yl)-
- CBNumber
- CB02984841
- Molecular Formula
- C52H60N6O12S
- Formula Weight
- 993.13
- MOL File
- 1562024-11-6.mol
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Hs 27 Property
- Boiling point:
- 1095.1±75.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- -196°C
- solubility
- DMSO: 125 mg/mL (125.86 mM)
- pka
- 9.33±0.20(Predicted)
- form
- Solid
- color
- Yellow to orange
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0114853
- Product name
- HS-27
- Purity
- 98.48%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0114853
- Product name
- HS-27
- Purity
- 98.48%
- Packaging
- 10mg
- Price
- $580
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0114853
- Product name
- HS-27
- Purity
- 98.48%
- Packaging
- 25mg
- Price
- $1100
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0114853
- Product name
- HS-27
- Purity
- 98.48%
- Packaging
- 50mg
- Price
- $1700
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0114853
- Product name
- HS-27
- Purity
- 98.48%
- Packaging
- 100mg
- Price
- $2500
- Updated
- 2021/12/16
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Hs 27 Chemical Properties,Usage,Production
Biological Activity
HS-27, a fluorescent Hsp90 inhibitor, detects Hsp90 expression on the surface of intact tissue specimens. It consists of the core elements of SNX-5422, an Hsp90 inhibitor linked via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC) that binds to peripherally expressed Hsp90 combine.
in vitro
HS-27 labels all receptor subtypes of breast cancer, but not normal cells, and specifically binds to Hsp90 expressed on the surface of breast cancer cells before being internalized.
target
HSP90
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Hs 27 Preparation Products And Raw materials
Raw materials
Preparation Products
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