ChemicalBook > CAS DataBase List > cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole
cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole
- Product Name
- cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole
- CAS No.
- 442656-02-2
- Chemical Name
- cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole
- Synonyms
- AG-205;AG-205 (AG205;AG-205 >=98% (HPLC);cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole;Ethanone, 2-[[1-(4-chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-;cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone
- CBNumber
- CB02985116
- Molecular Formula
- C22H23ClN6OS
- Formula Weight
- 454.98
- MOL File
- 442656-02-2.mol
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cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Property
- storage temp.
- 2-8°C
- solubility
- Soluble to 50 mM in DMSO
- form
- powder
- color
- off-white to brown
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- A1487
- Product name
- AG-205
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $210
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- A1487
- Product name
- AG-205
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $322
- Updated
- 2024/03/01
Tocris
- Product number
- 6242
- Product name
- AG205
- Purity
- ≥98%(HPLC)
- Packaging
- 25
- Price
- $573
- Updated
- 2021/12/16
Tocris
- Product number
- 6242
- Product name
- AG205
- Purity
- ≥98%(HPLC)
- Packaging
- 5
- Price
- $147
- Updated
- 2021/12/16
AK Scientific
- Product number
- SYN5581
- Product name
- AG-205
- Packaging
- 100mg
- Price
- $1660
- Updated
- 2021/12/16
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cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Chemical Properties,Usage,Production
Uses
AG-205 has been used to investigate the neuroprotective effects of norgestrel on stressed photoreceptors. It has also been used to study the effect of blocking progesterone receptor membrane component 1 in 661W cells.
Biochem/physiol Actions
AG-205 is a Pgrmc1 (progesterone receptor membrane component 1) inhibitor. AG-205 alters the spectroscopic properties of the Pgrmc1-heme complex. AG-205 inhibits cancer cell viability and cancer cell progression. acting preferentially on Pgrmc1-expressing cells.
storage
Store at +4°C
cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Preparation Products And Raw materials
Raw materials
Preparation Products
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cis-5-({[1-(4-chlorophenyl)-1H-tetraazol-5-yl]sulfanyl}acetyl)-2,8-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole Suppliers
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