ChemicalBook > CAS DataBase List > Cetrimide

Cetrimide

Product Name
Cetrimide
CAS No.
8044-71-1
Chemical Name
Cetrimide
Synonyms
TTAB;Myristyltrimethylammonium bromide;cetavlon;Cetrimidum;TRIMETHYLMYRISTYLAMMONIUM BROMIDE;cetraol;morphans;Cetavlex;Cradocap;Zetrimid
CBNumber
CB0299765
Molecular Formula
C17H38BrN
Formula Weight
336.39
MOL File
8044-71-1.mol
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Cetrimide Property

Melting point:
245-250 °C(lit.)
solubility 
H2O: 10 % (w/v)
CAS DataBase Reference
8044-71-1(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34-20/21/22
Safety Statements 
26-36/37/39-45-28
RIDADR 
UN 3263 8/PG 2
WGK Germany 
3
RTECS 
BS5776000
3
HS Code 
29181100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H314Causes severe skin burns and eye damage

H332Harmful if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological
Product number
290620
Product name
Tetradecyltrimethylammonium bromide
Packaging
100g
Price
$333
Updated
2021/12/16
Ambeed
Product number
A836788
Product name
N,N,N-Trimethyltetradecan-1-aminiumbromide
Purity
98%
Packaging
100g
Price
$7
Updated
2021/12/16
Ambeed
Product number
A836788
Product name
N,N,N-Trimethyltetradecan-1-aminiumbromide
Purity
98%
Packaging
1kg
Price
$37
Updated
2021/12/16
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Cetrimide Chemical Properties,Usage,Production

Chemical Properties

White or almost white, voluminous, free-flowing powder.

Chemical Properties

Cetrimide is a white to creamy white, free-flowing powder, with a faint but characteristic odor and a bitter, soapy taste.

Uses

antiinfectives

Production Methods

Cetrimide is prepared by the condensation of suitable alkyl bromides and trimethylamine.

Definition

ChEBI: Cetrimide is an organic molecular entity.

Pharmaceutical Applications

Cetrimide is a quaternary ammonium compound that is used in cosmetics and pharmaceutical formulations as an antimicrobial preservative. It may also be used as a cationic surfactant. In eye-drops, it is used as a preservative at a concentration of 0.005% w/v. Therapeutically, cetrimide is used in relatively high concentrations, generally as 0.1–1.0% w/v aqueous solutions, cream or spray as a topical antiseptic for skin, burns, and wounds.(1) Solutions containing up to 10% w/v cetrimide are used as shampoos to remove the scales in seborrheic dermatitis. Cetrimide is also used as a cleanser and disinfectant for hard contact lenses, although it should not be used on soft lenses; as an ingredient of cetrimide emulsifying wax, and in o/w creams (e.g. cetrimide cream).

Safety

Most adverse effects reported relate to the therapeutic use of cetrimide. If ingested orally, cetrimide and other quaternary ammonium compounds can cause nausea, vomiting, muscle paralysis, CNS depression, and hypotension; concentrated solutions may cause esophageal damage and necrosis. The fatal oral human dose is estimated to be 1.0–3.0 g.
At the concentrations used topically, solutions do not generally cause irritation, although concentrated solutions have occasionally been reported to cause burns. Cases of hypersensitivity have been reported following repeated application.
Adverse effects that have been reported following irrigation of hydatid cysts with cetrimide solution include chemical peritonitis, methemoglobinemia with cyanosis, and metabolic disorders.

storage

Cetrimide is chemically stable in the dry state, and also in aqueous solution at ambient temperatures. Aqueous solutions may be sterilized by autoclaving. Water containing metal ions and organic matter may reduce the antimicrobial activity of cetrimide.
The bulk material should be stored in a well-closed container in a cool, dry place.

Incompatibilities

Incompatible with soaps, anionic surfactants, high concentrations of nonionic surfactants, bentonite, iodine, phenylmercuric nitrate, alkali hydroxides, and acid dyes. Aqueous solutions react with metals.

Regulatory Status

Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Cetrimide is on the list of ‘Existing Active Substances’ on the market in the Europe, and is registered according to REACH regulation. Cetrimide is not present in any approved product in the USA.

Cetrimide Preparation Products And Raw materials

Raw materials

Preparation Products

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Cetrimide Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Xiamen Pioneer Technology Co., Ltd
Tel
13850073005
Fax
0592-3776077
Email
13939264@qq.com
Country
China
ProdList
50
Advantage
64
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2045
Advantage
56
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11578
Advantage
59
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
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View Lastest Price from Cetrimide manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Cetrimide 8044-71-1
Price
US $1000.00-400.00/ton
Min. Order
1ton
Purity
99%
Supply Ability
5000
Release date
2024-08-12
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Cetrimide 8044-71-1
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-29
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cetrimide 8044-71-1
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min; BP/USP
Supply Ability
10 TONS
Release date
2021-06-17

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