ChemicalBook > CAS DataBase List > 4-Ethylresorcinol

4-Ethylresorcinol

Product Name
4-Ethylresorcinol
CAS No.
2896-60-8
Chemical Name
4-Ethylresorcinol
Synonyms
KO 11;4-Ethyl Resorcin;5-Ethylresorcinol;4-ETHYLRESORCINOL;6-Ethylresorcinol;Resorcinol, 4-ethyl-;Ethyl 1,3-benzenediol;4-ethyl-3-benzenediol;4-Ethylresorcinol,98%;4-Ethylresorcinol 98%
CBNumber
CB0300724
Molecular Formula
C8H10O2
Formula Weight
138.16
MOL File
2896-60-8.mol
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4-Ethylresorcinol Property

Melting point:
95-98 °C (lit.)
Boiling point:
155 °C / 10mmHg
Density 
1.0742 (rough estimate)
refractive index 
1.5231 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Solubility in methanol; almost transparency. Soluble in alcohol.
form 
Crystalline Powder
pka
10.06±0.10(Predicted)
color 
Slightly beige
BRN 
1238231
InChIKey
VGMJYYDKPUPTID-UHFFFAOYSA-N
LogP
1.731 (est)
CAS DataBase Reference
2896-60-8(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Benzenediol, 4-ethyl-(2896-60-8)
EPA Substance Registry System
4-Ethylresorcinol (2896-60-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
TSCA 
Yes
HS Code 
29072100
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E48200
Product name
4-Ethylresorcinol
Purity
98%
Packaging
25g
Price
$412
Updated
2024/03/01
TCI Chemical
Product number
D0579
Product name
4-Ethylresorcinol
Purity
>98.0%(GC)
Packaging
5g
Price
$55
Updated
2024/03/01
TCI Chemical
Product number
D0579
Product name
4-Ethylresorcinol
Purity
>98.0%(GC)
Packaging
25g
Price
$149
Updated
2024/03/01
Alfa Aesar
Product number
B21575
Product name
4-Ethylresorcinol, 98%
Packaging
5g
Price
$53.65
Updated
2024/03/01
Alfa Aesar
Product number
B21575
Product name
4-Ethylresorcinol, 98%
Packaging
25g
Price
$167.65
Updated
2024/03/01
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4-Ethylresorcinol Chemical Properties,Usage,Production

Description

4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol has hypopigmentation effects.4-Ethylresorcinol attenuates the mRNA and protein expression of tyrosinase-related protein (TRP)-2, and has an antioxidant effect through the inhibition of lipid peroxidation. 4-Ethylresorcinol is a derivative of resorcinol, which acts as a substrate for tyrosinase. 4-Ethylresorcinol is a derivative of resorcinol.

Chemical Properties

slightly beige crystalline powder

Uses

It is employed as an active pharmaceutical intermediate.

Definition

ChEBI: 4-Ethylresorcinol is a member of resorcinols.

Synthesis Reference(s)

Synthetic Communications, 15, p. 1315, 1985 DOI: 10.1080/00397918508077280

Synthesis

The synthesis of 4-Ethylresorcinol is as follows:
In a three necked round bottom flask (equipped with a condensor, additional funnel and mechanical stirrer) was added 15.2 g of a combination of Raney Nickel and Ni supported on silica. (50: 50). 100 ml of a mixture of 50: 50 ethanol: water was added and the reaction was heated at reflux conditions. 15.2 g of 2,4-dihydroxy acetophenone in 100 ml of water: ethanol and 10 ml of acetic acid was placed in the additional funnel and slowly added to the mixture (dropwise). The reaction was filtered through a milipore filter to give a pale yellow solution. Concentration of this solution in vacuo gave a solid. This solid was crystalized from 1,2-dichloroethane to give 4-ethyl resorcinol in 80% isolated yield. 

4-Ethylresorcinol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Ethylresorcinol Suppliers

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View Lastest Price from 4-Ethylresorcinol manufacturers

Shandong Deshang Chemical Co., Ltd.
Product
4-Ethylresorcinol 2896-60-8
Price
US $5.90-3.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 tons
Release date
2024-06-26
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
4-Ethylresorcinol 2896-60-8
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99%
Supply Ability
20tons
Release date
2024-01-16
Hebei Weibang Biotechnology Co., Ltd
Product
4-Ethylresorcinol 2896-60-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-11-15

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