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Choline bicarbonate

Product Name
Choline bicarbonate
CAS No.
78-73-9
Chemical Name
Choline bicarbonate
Synonyms
DK910;CHOLINE BICARBONATE;CHOLINE BICARBONATE SALT;CHOLINE HYDROGEN CARBONATE;choline bicarbonate solution;CHOLINEBICARBONATE,75%SOLUTION;Choline bicarbonate-13C solution;2-Methyl-28-nitrobenzyl&chloride;CHOLINE BICARBONATE APPROX. 80% AQUE;CHOLINE BICARBONATE 75 WT. % SOLUTION &
CBNumber
CB0301110
Molecular Formula
C6H15NO4
Formula Weight
165.19
MOL File
78-73-9.mol
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Choline bicarbonate Property

Density 
1.17 g/mL at 25 °C (lit.)
vapor pressure 
23.904hPa at 25℃
refractive index 
n20/D 1.45
storage temp. 
2-8°C
solubility 
Methanol (Sparingly), Water (Soluble)
form 
Colourless Solution
Water Solubility 
750g/L at 20℃
InChIKey
DQKGOGJIOHUEGK-UHFFFAOYSA-M
CAS DataBase Reference
78-73-9(CAS DataBase Reference)
EPA Substance Registry System
Choline carbonate (1:1) (78-73-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C7519
Product name
Choline bicarbonate
Purity
~80% in H2O
Packaging
100ml
Price
$183
Updated
2024/03/01
Sigma-Aldrich
Product number
C7519
Product name
Choline bicarbonate
Purity
~80% in H2O
Packaging
250ml
Price
$373
Updated
2024/03/01
Sigma-Aldrich
Product number
C7519
Product name
Choline bicarbonate
Purity
~80% in H2O
Packaging
500ml
Price
$642
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
NUT0000528
Product name
CHOLINE BICARBONATE
Purity
95.00%
Packaging
100G
Price
$2836.48
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
NUT0000528
Product name
CHOLINE BICARBONATE
Purity
95.00%
Packaging
250G
Price
$5162.2
Updated
2021/12/16
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Choline bicarbonate Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid.Miscible with water.

Uses

Choline, a water soluble essential nutrient, is used by the body to make phosphatidylcholine phosphatides and neurotransmitter such as acetylcholine. Choline is used to study a wide range of biological processes from stem cell development to neurological disease studies. Also, An alkaline intermediate useful for preparing salts.

Uses

Choline Bicarbonate is compound is used for protein delivery, Alkaline catalyst, intermediate for choline salts and surfactants.

Reactions

[1CA:3PE] - (1:2) Choline 3-Pentenoate Synthesis

An oil bath was heated to approximately 60°C and the stirrer on the hot plate was adjusted to 410 RPM. 3.5022g of 3-Pentenoic acid (MW: 100.12g/mol) were weighed and placed in a 500 mL RBF. 3.6254g of Choline Bicarbonate (MW: 165.19g/mol) were weighed and added to the RBF in a drop-wise manner using a glass Pasteur pipette. Less than 1 mL of milli-Q water was used to rinse the master pipette and weighing materials, the milli-Q was then added to the RBF. The mixture was left stirring on heat overnight for approximately 24 hours. The mixture was then placed on the rotary-evaporator and set to 15 mbar for just over 1 hour in order to evaporate any remaining solvents. The mass of the final product was weighed and noted; 4.5891g of [1CA:3PE] were obtained. The solution was then placed in the vacuum oven set at 60°C for over 48 hours with the top left off. Time sensitivity during this step was not as imperative as other steps since the purpose of this step was to dry out any remaining solvents or water in the IL. Once removed from the vacuum oven, the solution was reweighed and an NMR was obtained for characterization purposes. The final mass of [1CA:3PE] being 4.4934g, resulting in a total percent yield of 86.74%. 1H NMR (400 MHz, DMSO) δ 9.47 (s, 1H), 5.52 (dtd, J = 14.0, 7.0, 1.8 Hz, 2H), 5.37 (dq, J = 13.3, 6.3 Hz, 2H), 3.84 (dq, J = 5.8, 2.7 Hz, 2H), 3.44 (dd, J = 6.1, 3.9 Hz, 2H), 3.14 (s, 9H), 2.80 (d, J = 7.0 Hz, 4H), 1.61 (dd, J = 6.4, 1.8 Hz, 6H).
[1] GALLOWAY J D. The Synthesis and Characterization of Ionic Liquids using Nitrogen-Based Cations for Transdermal Delivery[C]. 2022.

Hazard

Choline bicarbonate can cause skin and eye irritation, as well as potential respiratory irritation.

Biochem/physiol Actions

Acyl group acceptor

Choline bicarbonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Choline bicarbonate Suppliers

Jinan Rouse Industry Co., Ltd.
Tel
0531-0531-82929600 18615510361
Fax
053182921652
Email
sale@rousechem.com
Country
China
ProdList
176
Advantage
58
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
Advantage
55
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9649
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Kono Chem Co.,Ltd
Tel
15829389671
Fax
029-86107037
Email
info@konochemical.com
Country
China
ProdList
554
Advantage
55
Hangzhou Dingyan Chem Co., LTD
Tel
0571-87157530-8002 15267169049
Fax
0571-87156470
Email
sales@dingyanchem.com
Country
China
ProdList
2190
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10011
Advantage
58
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
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View Lastest Price from Choline bicarbonate manufacturers

Henan Fengda Chemical Co., Ltd
Product
Choline bicarbonate 78-73-9
Price
US $8.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-22
Zhuozhou Wenxi import and Export Co., Ltd
Product
Choline bicarbonate 78-73-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
Choline bicarbonate 78-73-9
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2019-12-25

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