ChemicalBook > CAS DataBase List > 2,6-Dimethoxybenzoic acid

2,6-Dimethoxybenzoic acid

Product Name
2,6-Dimethoxybenzoic acid
CAS No.
1466-76-8
Chemical Name
2,6-Dimethoxybenzoic acid
Synonyms
AKOS BBS-00003742;RARECHEM AL BO 1076;2,6-Dimethoxybenzoic;Novobiocin Impurity 4;2,6-dimethoxy-benzoicaci;2,6-DIMETHOXYBENZOIC ACID;Benzoicacid,2,6-dimethoxy-;2,6-DimethoxybenzoicAcid>2,6-Dimethoxybenzoic acid,99%;γ-Resorcylic acid diMethyl ether
CBNumber
CB0303008
Molecular Formula
C9H10O4
Formula Weight
182.17
MOL File
1466-76-8.mol
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2,6-Dimethoxybenzoic acid Property

Melting point:
185-187 °C (lit.)
Boiling point:
275.56°C (rough estimate)
Density 
1.2481 (rough estimate)
refractive index 
1.4500 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
14.7g/l soluble
form 
Crystalline Powder
pka
pK1:3.44 (25°C)
color 
White to off-white
Water Solubility 
0.35 g/100 mL (25 ºC)
BRN 
2212190
InChIKey
MBIZFBDREVRUHY-UHFFFAOYSA-N
LogP
0.660
CAS DataBase Reference
1466-76-8(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 2,6-dimethoxy-(1466-76-8)
EPA Substance Registry System
Benzoic acid, 2,6-dimethoxy- (1466-76-8)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
DG8598725
TSCA 
Yes
HS Code 
29189010
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D131601
Product name
2,6-Dimethoxybenzoic acid
Purity
98%
Packaging
25g
Price
$66.9
Updated
2023/06/20
TCI Chemical
Product number
D1959
Product name
2,6-Dimethoxybenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
D1959
Product name
2,6-Dimethoxybenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$399
Updated
2023/06/20
Alfa Aesar
Product number
A14418
Product name
2,6-Dimethoxybenzoic acid, 99%
Packaging
25g
Price
$40.6
Updated
2024/03/01
Alfa Aesar
Product number
A14418
Product name
2,6-Dimethoxybenzoic acid, 99%
Packaging
100g
Price
$104
Updated
2024/03/01
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2,6-Dimethoxybenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder. Hardly soluble in water, soluble in alkali and organic solvents, such as benzene and toluene.

Uses

2,6-Dimethoxybenzoic Acid is used in the synthesis of indoles as well as coumarins related to Novobiocin (N888500), used as potent inhibitors of heat-shock protein 90 in the treatment of breast cancer.

Preparation

2,6-Dimethoxybenzoic acid is the key intermediate in the preparation of gamma-resorcylic acid which has been described as having activity against rheumatic fever.
The Preparation of 2,6-Dimethoxybenzoic Acid
Cite this: J. Org. Chem. 1956, 21, 3, 368–369
Publication Date:March 1, 1956
https://doi.org/10.1021/jo01109a604

Definition

ChEBI: 2,6-Dimethoxybenzoic acid is a member of benzenes and a carbonyl compound. It is a polyphenol compound found in foods of plant origin.

Synthesis Reference(s)

Synthetic Communications, 22, p. 13, 1992 DOI: 10.1080/00397919208021074

Flammability and Explosibility

Not classified

Purification Methods

Crystallise the acid from water or 1,1-dichloroethane (m 187.5-188.5o). [Beilstein 10 H 388, 10 I 185, 10 II 259, 10 III 1401, 10 IV 1456.]

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2,6-Dimethoxybenzoic acid Suppliers

Shanghai Arbor Chemical Co., Ltd.
Tel
021-021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
922
Advantage
55
Wuhan kamik Technology Co., Ltd
Tel
18062587608
Email
201981259@qq.com
Country
China
ProdList
7716
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
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View Lastest Price from 2,6-Dimethoxybenzoic acid manufacturers

Hebei Duling International Trade Co. LTD
Product
2,6-Dimethoxybenzoic acid 1466-76-8
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2023-03-21
Hebei Mojin Biotechnology Co., Ltd
Product
2,6-Dimethoxybenzoic acid 1466-76-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-30
Hebei Guanlang Biotechnology Co,.LTD
Product
2,6-Dimethoxybenzoic acid 1466-76-8
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2023-06-06

1466-76-8, 2,6-Dimethoxybenzoic acidRelated Search:


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