ChemicalBook > CAS DataBase List > 10β,17β-dihydroxyestra-1,4-dien-3-one
10β,17β-dihydroxyestra-1,4-dien-3-one
- Product Name
- 10β,17β-dihydroxyestra-1,4-dien-3-one
- CAS No.
- 549-02-0
- Chemical Name
- 10β,17β-dihydroxyestra-1,4-dien-3-one
- Synonyms
- 10β;DHED;4-dien-3-one;17β-dihydroxyestra-1;10β,17β-dihydroxyestra-1,4-dien-3-one;10,17β-Dihydroxy-estra-1,4-dien-3-one;10β,17β-dihydroxyestra-1,4-dien-3-one;10b,17b-Dihydroxy-estra-1,4-dien-3-one;Estra-1,4-dien-3-one, 10,17-dihydroxy-, (17β)-;10β,17β dihydroxyestra 1,4 dien 3 one,10β,17βdihydroxyestra1,4dien3one
- CBNumber
- CB03037801
- Molecular Formula
- C18H24O3
- Formula Weight
- 288.39
- MOL File
- 549-02-0.mol
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10β,17β-dihydroxyestra-1,4-dien-3-one Property
- Melting point:
- 217-219 °C(Solv: ethyl acetate (141-78-6))
- Boiling point:
- 485.3±45.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 10mg/mL, clear
- form
- powder
- pka
- 12.35±0.60(Predicted)
- color
- white to light brown
- optical activity
- [α]/D -20 to -30°, c = 1 in methanol
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1642
- Product name
- DHED
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $105
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- SML1642
- Product name
- DHED
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $424
- Updated
- 2023/06/20
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10β,17β-dihydroxyestra-1,4-dien-3-one Chemical Properties,Usage,Production
Uses
DHED has been used to induce an increase of estrogen levels in 3K transgenic mice with Parkinson′s disease (PD)-like motor syndrome.
Biochem/physiol Actions
DHED is a substrate for nicotinamide adenine dinucleotide phosphate (NADPH)-dependent dehydrogenase/reductase. Its expression in the brain is correlated to neuroprotection functionality.
10β,17β-dihydroxyestra-1,4-dien-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
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