ChemicalBook > CAS DataBase List > 10β,17β-dihydroxyestra-1,4-dien-3-one

10β,17β-dihydroxyestra-1,4-dien-3-one

Product Name
10β,17β-dihydroxyestra-1,4-dien-3-one
CAS No.
549-02-0
Chemical Name
10β,17β-dihydroxyestra-1,4-dien-3-one
Synonyms
10β;DHED;4-dien-3-one;17β-dihydroxyestra-1;10β,17β-dihydroxyestra-1,4-dien-3-one;10,17β-Dihydroxy-estra-1,4-dien-3-one;10β,17β-dihydroxyestra-1,4-dien-3-one;10b,17b-Dihydroxy-estra-1,4-dien-3-one;Estra-1,4-dien-3-one, 10,17-dihydroxy-, (17β)-;10β,17β dihydroxyestra 1,4 dien 3 one,10β,17βdihydroxyestra1,4dien3one
CBNumber
CB03037801
Molecular Formula
C18H24O3
Formula Weight
288.39
MOL File
549-02-0.mol
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10β,17β-dihydroxyestra-1,4-dien-3-one Property

Melting point:
217-219 °C(Solv: ethyl acetate (141-78-6))
Boiling point:
485.3±45.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 10mg/mL, clear
form 
powder
pka
12.35±0.60(Predicted)
color 
white to light brown
optical activity
[α]/D -20 to -30°, c = 1 in methanol
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1642
Product name
DHED
Purity
≥98% (HPLC)
Packaging
5MG
Price
$105
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1642
Product name
DHED
Purity
≥98% (HPLC)
Packaging
25MG
Price
$424
Updated
2023/06/20
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10β,17β-dihydroxyestra-1,4-dien-3-one Chemical Properties,Usage,Production

Uses

DHED has been used to induce an increase of estrogen levels in 3K transgenic mice with Parkinson′s disease (PD)-like motor syndrome.

Biochem/physiol Actions

DHED is a substrate for nicotinamide adenine dinucleotide phosphate (NADPH)-dependent dehydrogenase/reductase. Its expression in the brain is correlated to neuroprotection functionality.

10β,17β-dihydroxyestra-1,4-dien-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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10β,17β-dihydroxyestra-1,4-dien-3-one Suppliers

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549-02-0, 10β,17β-dihydroxyestra-1,4-dien-3-oneRelated Search:


  • 10β,17β-dihydroxyestra-1,4-dien-3-one
  • DHED
  • Estra-1,4-dien-3-one, 10,17-dihydroxy-, (17β)-
  • 10,17β-Dihydroxy-estra-1,4-dien-3-one
  • 10β
  • 10β,17β-dihydroxyestra-1,4-dien-3-one
  • 17β-dihydroxyestra-1
  • 4-dien-3-one
  • 10β,17β dihydroxyestra 1,4 dien 3 one,10β,17βdihydroxyestra1,4dien3one
  • 10b,17b-Dihydroxy-estra-1,4-dien-3-one
  • 549-02-0