N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
- Product Name
- N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
- CAS No.
- 778274-97-8
- Chemical Name
- N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
- Synonyms
- MDK74978;INVIVO74978;MDK74978;MDK-74978;Multi-kinase inhibitor 1;Multi-kinase inhibitor I;MDK74978(Multi-kinase inhibitor);MDK 74978. Multi-kinase inhibitor I;Multi-kinase inhibitor 1, 10 mM in DMSO;MDK74978; MDK-74978; MDK 74978. MULTI-KINASE INHIBITOR I;N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
- CBNumber
- CB03038833
- Molecular Formula
- C20H17F3N4O3
- Formula Weight
- 418.37
- MOL File
- 778274-97-8.mol
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Property
- storage temp.
- Store at 0-8 °C
- form
- Solid
- color
- Off-white to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- DC10570
- Product name
- MDK74978(Multi-kinaseinhibitor)
- Purity
- >98%
- Packaging
- 100mg
- Price
- $600
- Updated
- 2021/12/16
- Product number
- CM322999
- Product name
- N-(2-Hydroxyethyl)-4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide
- Purity
- 95%
- Packaging
- 1g
- Price
- $617
- Updated
- 2021/12/16
- Product number
- CD11058139
- Product name
- N-(2-Hydroxyethyl)-4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide
- Purity
- 95+%
- Packaging
- 1g
- Price
- $660
- Updated
- 2021/12/16
- Product number
- DC10570
- Product name
- MDK74978(Multi-kinaseinhibitor)
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1080
- Updated
- 2021/12/16
- Product number
- DC10570
- Product name
- MDK74978(Multi-kinaseinhibitor)
- Purity
- >98%
- Packaging
- 1g
- Price
- $2160
- Updated
- 2021/12/16
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Chemical Properties,Usage,Production
Uses
Multi-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl[1].
IC 50
PDGFR; Bcr-Abl
References
[1] Qiang Ding, et al. Novel compounds and compositions as protein kinase inhibitors. WO2004089286A2.
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Preparation Products And Raw materials
Raw materials
Preparation Products
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Suppliers
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