ChemicalBook > CAS DataBase List > N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

Product Name
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
CAS No.
778274-97-8
Chemical Name
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
Synonyms
MDK74978;INVIVO74978;MDK74978;MDK-74978;Multi-kinase inhibitor 1;Multi-kinase inhibitor I;MDK74978(Multi-kinase inhibitor);MDK 74978. Multi-kinase inhibitor I;Multi-kinase inhibitor 1, 10 mM in DMSO;MDK74978; MDK-74978; MDK 74978. MULTI-KINASE INHIBITOR I;N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
CBNumber
CB03038833
Molecular Formula
C20H17F3N4O3
Formula Weight
418.37
MOL File
778274-97-8.mol
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N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Property

storage temp. 
Store at 0-8 °C
form 
Solid
color 
Off-white to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
44005
Product name
MDK74978
Purity
≥98%
Packaging
5mg
Price
$98
Updated
2026/04/30
Cayman Chemical
Product number
44005
Product name
MDK74978
Purity
≥98%
Packaging
10mg
Price
$148
Updated
2026/04/30
Cayman Chemical
Product number
44005
Product name
MDK74978
Purity
≥98%
Packaging
25mg
Price
$318
Updated
2026/04/30
Cayman Chemical
Product number
44005
Product name
MDK74978
Purity
≥98%
Packaging
50mg
Price
$490
Updated
2026/04/30
ApexBio Technology
Product number
A9956
Product name
Multi-kinase inhibitor 1
Packaging
1mg
Price
$50
Updated
2026/05/06
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N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Chemical Properties,Usage,Production

Uses

Multi-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl[1].

IC 50

PDGFR; Bcr-Abl

References

[1] Qiang Ding, et al. Novel compounds and compositions as protein kinase inhibitors. WO2004089286A2.

N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Suppliers

Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-84699383-8003;025-846993838003-8003 18013301593;18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3293
Advantage
55
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89686
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9710
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 19372819560
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9625
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Nanjing KaiMubo Pharmaceutical Co., Ltd.
Tel
025-66162170
Fax
025-66162170
Country
China
ProdList
7181
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3290
Advantage
58

778274-97-8, N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamideRelated Search:


  • N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
  • Multi-kinase inhibitor I
  • MDK74978(Multi-kinase inhibitor)
  • MDK74978
  • MDK 74978. Multi-kinase inhibitor I
  • MDK74978; MDK-74978; MDK 74978. MULTI-KINASE INHIBITOR I
  • MDK74978;MDK-74978
  • Benzamide, N-(2-hydroxyethyl)-4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-
  • Multi-kinase inhibitor 1
  • INVIVO74978
  • Platelet-derived growth factor receptor,inhibit,Bcr-Abl,SCFR,CD117,Multi-kinase inhibitor 1,c-Kit,Multi kinase inhibitor 1,PDGFR,Multikinase inhibitor 1,Inhibitor
  • Multi-kinase inhibitor 1, 10 mM in DMSO
  • 778274-97-8