ChemicalBook > CAS DataBase List > N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide

Product Name
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
CAS No.
778274-97-8
Chemical Name
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
Synonyms
MDK74978;INVIVO74978;MDK74978;MDK-74978;Multi-kinase inhibitor 1;Multi-kinase inhibitor I;MDK74978(Multi-kinase inhibitor);MDK 74978. Multi-kinase inhibitor I;Multi-kinase inhibitor 1, 10 mM in DMSO;MDK74978; MDK-74978; MDK 74978. MULTI-KINASE INHIBITOR I;N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
CBNumber
CB03038833
Molecular Formula
C20H17F3N4O3
Formula Weight
418.37
MOL File
778274-97-8.mol
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N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Property

storage temp. 
Store at 0-8 °C
form 
Solid
color 
Off-white to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

DC Chemicals
Product number
DC10570
Product name
MDK74978(Multi-kinaseinhibitor)
Purity
>98%
Packaging
100mg
Price
$600
Updated
2021/12/16
Chemenu
Product number
CM322999
Product name
N-(2-Hydroxyethyl)-4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide
Purity
95%
Packaging
1g
Price
$617
Updated
2021/12/16
Crysdot
Product number
CD11058139
Product name
N-(2-Hydroxyethyl)-4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide
Purity
95+%
Packaging
1g
Price
$660
Updated
2021/12/16
DC Chemicals
Product number
DC10570
Product name
MDK74978(Multi-kinaseinhibitor)
Purity
>98%
Packaging
250mg
Price
$1080
Updated
2021/12/16
DC Chemicals
Product number
DC10570
Product name
MDK74978(Multi-kinaseinhibitor)
Purity
>98%
Packaging
1g
Price
$2160
Updated
2021/12/16
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N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Chemical Properties,Usage,Production

Uses

Multi-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl[1].

IC 50

PDGFR; Bcr-Abl

References

[1] Qiang Ding, et al. Novel compounds and compositions as protein kinase inhibitors. WO2004089286A2.

N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Suppliers

Nanjing Dulai Biotechnology Co., Ltd.
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025-846993838003-8003 18013301590
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China
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Tel
13621943973
Fax
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sales@shjiyipharmatech.com
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China
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Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
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China
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Tianjin Kailiqi Biotechnology Co., Ltd.
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Fax
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Shanghai Chaolan Chemical Technology Center
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Fax
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Amadis Chemical Company Limited
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778274-97-8, N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamideRelated Search:


  • N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
  • Multi-kinase inhibitor I
  • MDK74978(Multi-kinase inhibitor)
  • MDK74978
  • MDK 74978. Multi-kinase inhibitor I
  • MDK74978; MDK-74978; MDK 74978. MULTI-KINASE INHIBITOR I
  • MDK74978;MDK-74978
  • Benzamide, N-(2-hydroxyethyl)-4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-
  • Multi-kinase inhibitor 1
  • INVIVO74978
  • Platelet-derived growth factor receptor,inhibit,Bcr-Abl,SCFR,CD117,Multi-kinase inhibitor 1,c-Kit,Multi kinase inhibitor 1,PDGFR,Multikinase inhibitor 1,Inhibitor
  • Multi-kinase inhibitor 1, 10 mM in DMSO
  • 778274-97-8