Benzyl-PEG8-azide

Product Name: Benzyl-PEG8-azide
CAS No.: 868594-42-7
Chemical Name: Benzyl-PEG8-azide
Synonyms: Benzyl-PEG8-N3;Benzyl-PEG7-N3;Benzyl-PEG7-azide;Benzyl-PEG8-azide;22-Azido-1-phenyl-2,5,8,11,14,17,20-heptaoxadocosane;2,5,8,11,14,17,20-Heptaoxadocosane, 22-azido-1-phenyl-
CBNumber: CB03048700
Molecular Formula: C21H35N3O7
Formula Weight: 441.53
MOL File: 868594-42-7.mol

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Hazard and Precautionary Statements (GHS)

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Benzyl-PEG8-azide Chemical Properties,Usage,Production

Uses

Benzyl-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Benzyl-PEG7-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Biological Activity

Benzyl-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Benzyl-PEG8-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzyl-PEG8-azide Suppliers

China 16 United States 1 Global 17

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
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Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
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Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
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Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
Fax: 027-59218822
Email: 3207347307@qq.com
Country: CHINA
ProdList: 1238
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Shanghai Jiange Chemical Co., Ltd.

Tel: 15921040873
Email: 1434142450@qq.com
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ProdList: 7649
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Shaanxi borno biotechnology co., LTD

Tel: +86-13759708231
Email: asherw9@hotmail.com
Country: China
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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

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View Lastest Price from Benzyl-PEG8-azide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Benzyl-PEG7-N3 868594-42-7
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-25

868594-42-7, Benzyl-PEG8-azideRelated Search:

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Benzyl-PEG8-azide

Benzyl-PEG7-azide

Benzyl-PEG7-N3

Benzyl-PEG8-N3

2,5,8,11,14,17,20-Heptaoxadocosane, 22-azido-1-phenyl-

22-Azido-1-phenyl-2,5,8,11,14,17,20-heptaoxadocosane

868594-42-7