THP-PEG6-alcohol
- Product Name
- THP-PEG6-alcohol
- CAS No.
- 42607-87-4
- Chemical Name
- THP-PEG6-alcohol
- Synonyms
- THP-PEG7;HO-PEG6-THP;OH-PEG6-THP;THP-PEG6-OH;CAS_42607-87-4;THP-PEG6-alcohol;17-((Tetrahydro-2H-pyran-2-yl)oxy)-3,6,9,12,15-pentaoxaheptadecan-1-ol;3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-[(tetrahydro-2H-pyran-2-yl)oxy]-;THP-PEG6-OH/3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-[(tetrahydro-2H-pyran-2-yl)oxy]-
- CBNumber
- CB03049424
- Molecular Formula
- C17H34O8
- Formula Weight
- 366.45
- MOL File
- 42607-87-4.mol
THP-PEG6-alcohol Property
- Boiling point:
- 469.0±45.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- pka
- 14.36±0.10(Predicted)
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-21970
- Product name
- THP-PEG7
- Purity
- 98%
- Packaging
- 1g
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-21970
- Product name
- THP-PEG7
- Purity
- 98%
- Packaging
- 2g
- Price
- $570
- Updated
- 2021/12/16
- Product number
- BIPG1852
- Product name
- THP-PEG7
- Packaging
- 1g
- Price
- $740
- Updated
- 2021/12/16
- Product number
- BP-21970
- Product name
- THP-PEG7
- Purity
- 98%
- Packaging
- 5G
- Price
- $850
- Updated
- 2021/12/16
- Product number
- B-0720
- Product name
- THP-PEG6-OH
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $220
- Updated
- 2021/12/16
THP-PEG6-alcohol Chemical Properties,Usage,Production
Description
THP-PEG7 is a PEG linker containing a THP protecting group and a hydroxyl group. THP is acid labile and is commonly used for the protection of alcohol groups. The terminal hydroxyl group can be further reacted to derivatize the compound. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Uses
THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
IC 50
PEGs; Non-cleavable Linker
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
[2] Masahiro Tomita, et al. Antibody specifically recognizing resin plasticizer compound. WO2005105846A1.
THP-PEG6-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
THP-PEG6-alcohol Suppliers
- Tel
- 027-65563561
- Fax
- 86-27-59218822
- sales@borenpharm.com
- Country
- China
- ProdList
- 1245
- Advantage
- 55
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 10110
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- 021-68882955 17721395025
- Fax
- 021-68882955
- 2423903095@qq.com
- Country
- China
- ProdList
- 4991
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28785
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- 0371-55051623 18137891487
- Fax
- QQ:2853979817
- 2853979817@qq.com
- Country
- China
- ProdList
- 9988
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 571-86758373 +8613588754946
- Fax
- 0086-571-81131109
- sales@huarongpharm.com
- Country
- CHINA
- ProdList
- 3148
- Advantage
- 58
View Lastest Price from THP-PEG6-alcohol manufacturers
- Product
- OH-PEG6-THP 42607-87-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25