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Afatinib Impurity 4

Product Name
Afatinib Impurity 4
CAS No.
2512206-82-3
Chemical Name
Afatinib Impurity 4
Synonyms
Afatinib Impurity 4;4-Quinazolinamine, N-(3,4-dichlorophenyl)-7-fluoro-6-nitro-
CBNumber
CB03049752
Molecular Formula
C14H7Cl2FN4O2
Formula Weight
353.14
MOL File
2512206-82-3.mol
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Afatinib Impurity 4 Property

Boiling point:
513.4±50.0 °C(Predicted)
Density 
1.634±0.06 g/cm3(Predicted)
pka
5.16±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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Afatinib Impurity 4 Chemical Properties,Usage,Production

Uses

N-(3,4-Dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib (A355300); an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

Afatinib Impurity 4 Preparation Products And Raw materials

Raw materials

Preparation Products

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