ChemicalBook > CAS DataBase List > 2'-C-ethynyluridine

2'-C-ethynyluridine

Product Name: 2'-C-ethynyluridine
CAS No.: 188413-98-1
Chemical Name: 2'-C-ethynyluridine
Synonyms: EOS-61194;2'-C-ethynyluridine;Uridine, 2'-C-ethynyl-;2’-beta-C-Ethynyluridine;2'-beta-C-Ethynyluridine;1-((2R,3R,4R,5R)-3-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CBNumber: CB03051810
Molecular Formula: C11H12N2O6
Formula Weight: 268.22
MOL File: 188413-98-1.mol

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Hazard and Precautionary Statements (GHS)

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2'-C-ethynyluridine Chemical Properties,Usage,Production

Uses

2'-C-Ethynyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2'-C-Ethynyluridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-C-ethynyluridine Preparation Products And Raw materials

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188413-98-1, 2'-C-ethynyluridineRelated Search:

2'-C-ethynyluridine

1-((2R,3R,4R,5R)-3-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

EOS-61194

2'-beta-C-Ethynyluridine

Uridine, 2'-C-ethynyl-

2’-beta-C-Ethynyluridine

188413-98-1