Bromoacetamido-PEG4-NHS ester
- Product Name
- Bromoacetamido-PEG4-NHS ester
- CAS No.
- 1260139-70-5
- Chemical Name
- Bromoacetamido-PEG4-NHS ester
- Synonyms
- CAS_1260139-70-5;BrCH2CONH-PEG4-NHS ester;Bromoacetamido-PEG5-NHS ester;Bromoacetamido-PEG4-NHS ester;2,5-Dioxopyrrolidin-1-yl 1-bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate;4,7,10,13-Tetraoxa-16-azaoctadecanoic acid, 18-bromo-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB03053546
- Molecular Formula
- C17H27BrN2O9
- Formula Weight
- 483.31
- MOL File
- 1260139-70-5.mol
Bromoacetamido-PEG4-NHS ester Property
- storage temp.
- Storage temp. -20°C
- form
- Oil
- color
- Colorless to light yellow
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P331Do NOT induce vomiting.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D495563
- Product name
- 2,5-Dioxopyrrolidin-1-yl1-Bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oate
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- BP-20569
- Product name
- Bromoacetamido-PEG4-NHSester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-20569
- Product name
- Bromoacetamido-PEG4-NHSester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $485
- Updated
- 2021/12/16
- Product number
- BIPG1317
- Product name
- Bromoacetamido-PEG4- NHS ester
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
- Product number
- AS108042
- Product name
- Bromoacetamido-PEG4-NHSester
- Purity
- 94%
- Packaging
- 250mg
- Price
- $592
- Updated
- 2021/12/16
Bromoacetamido-PEG4-NHS ester Chemical Properties,Usage,Production
Description
Bromoacetamido-PEG4-NHS ester is a PEG linker containing a bromide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Bromoacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromoacetamido-PEG4-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
Bromoacetamido-PEG4-NHS ester Suppliers
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View Lastest Price from Bromoacetamido-PEG4-NHS ester manufacturers
- Product
- BrCH2CONH-PEG4-NHS ester 1260139-70-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25