ChemicalBook > CAS DataBase List > 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni

2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni

Product Name
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni
CAS No.
120511-92-4
Chemical Name
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni
Synonyms
Anastrozole Isomer;Anastrozole iMpurity G;Anastrozole EP Impurity G;Anastrozole Impurity 12（EP Impurity G）;Isoanastrozole(Anastrozole EP Impurity G);Anastrozole EP Impurity G (Anastrozole Isomer);f . 4-me th ylb e nze ne sulf oni c a c i d ,;Anastrozole Impurity 12（Anastrozole EP Impurity G）;2,2'-[5-(4H-1,2,4-triazol-4-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile);2,2'-[5-(4H-1,2,4-triazol-4-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile
CBNumber
CB03058521
Molecular Formula
C17H19N5
Formula Weight
293.37
MOL File
120511-92-4.mol
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2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni Property

Boiling point:
469.7±55.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.86±0.10(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I780025
Product name
Isoanastrozole
Packaging
10mg
Price
$185
Updated
2021/12/16
Matrix Scientific
Product number
158313
Product name
2,2'-[5-(4H-1,2,4-Triazol-4-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
Packaging
0.500g
Price
$120
Updated
2021/12/16
Matrix Scientific
Product number
158313
Product name
2,2'-[5-(4H-1,2,4-Triazol-4-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
Packaging
1g
Price
$150
Updated
2021/12/16
Crysdot
Product number
CD11332408
Product name
2,2'-(5-((4H-1,2,4-Triazol-4-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile)
Purity
97%
Packaging
5g
Price
$349
Updated
2021/12/16
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2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni Chemical Properties,Usage,Production

Uses

Isoanastrozole (Anastrozole EP Impurity G) is used in the preparation of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.

2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni Suppliers

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120511-92-4, 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneniRelated Search:

Anastrozole Dimer Impurity Anastrozole IMpurity (alfa1 , alfa1, alfa3, alfa3-TetraMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-1,3-BenzenediacetaMide) Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetaMide) Anastrozole iMpurityC Anastrozole IMpurity (2-(3-((1H-1,2,4-triazol-1-yl)Methyl)-5-(1-aMino-2-Methyl-1-oxopropan-2-yl)phenyl)-2-Methylpropanoi Anastrozole iMpurity D Anastrozole iMpurity E Anastrozole Anastrozole iMpurity A Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid) 5-(Hydroxymethyl)-alpha,alpha,alpha',alpha'-tetramethyl-1,3-benzenediacetonitrile 3,5-Bis(2-cyanoprop-2-yl)toluene Di-Destriazole Anastrozole DiMer IMpurity 3,5-Bis(bromomethyl)toluene Anastrozole Impurity 11 2-[3-CHLOROMETHYL-5-(CYANO-DIMETHYL-METHYL)-PHENYL]-2-METHYL-PROPIONITRILE 5-Methyl-1,3-benzenediacetonitrile Anastrozole N-glucuronide

  • 2,2'-[5-(4H-1,2,4-triazol-4-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
  • 2-[3-(1-cyano-1-methyl-ethyl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propanenitrile
  • 2-[3-(1-cyano-1-methylethyl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methylpropanenitrile
  • 2-[3-(1-cyano-1-methyl-ethyl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propionitrile
  • 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni
  • 2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methylpropanenitrile
  • Anastrozole Isomer
  • Anastrozole EP Impurity G
  • 2-[3-(2-cyanopropan-2-yl)-5-(1,5-dihydro-1,2,4-triazol-4-ylmethyl)phenyl]-2-methylpropanenitrile
  • Anastrozole iMpurity G
  • 2,2'-[5-(4H-1,2,4-triazol-4-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile
  • Anastrozole Impurity 12（EP Impurity G）
  • Anastrozole EP Impurity G (Anastrozole Isomer)
  • 1,3-Benzenediacetonitrile, α1,α1,α3,α3-tetramethyl-5-(4H-1,2,4-triazol-4-ylmethyl)-
  • 2-[3-(1-cyano-1-methyl-ethyl)-5-(4H-1,3,4-triazol-1-ylmethyl)phenyl]-2-methyl-propionitrile
  • Anastrozole Impurity 12（Anastrozole EP Impurity G）
  • 2-[3-(1-cyano-1-methylethyl)-5-[(4H-1,2,4-triazol-4- yl)methyl]phenyl]-2-methylpropanenitrile
  • Isoanastrozole(Anastrozole EP Impurity G)
  • f . 4-me th ylb e nze ne sulf oni c a c i d ,
  • 2,2'-(5-((4H-1,2,4-Triazol-4-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile) (Anastrozole Impurity)
  • 2,2'-(5-((4H-1,2,4-Triazol-4-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile)
  • 2,2'-(5-((4H-1,2,4-Triazol-4-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile) (Anastrozole Impurity)
  • 120511-92-4