ChemicalBook > CAS DataBase List > GSK-F1

GSK-F1

Product Name
GSK-F1
CAS No.
1402345-92-9
Chemical Name
GSK-F1
Synonyms
GSK-F1;CS-2666;rac-GSK-F1;PI4KA inhibitor-F1;GSK-F1, 10 mM in DMSO;5-[2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide;5-{2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]-3,4-dihydro-6-quinazolinyl}-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulfonamide;3-Pyridinesulfonamide, 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-;hepatitis C virus,Phosphoinositide 3-kinase,Inhibitor,HEK293-AT1 cells,GSK-F-1,PI4K,Phosphatidylinositol 4 kinases,GSK-F1,HCV,GSKF1,COS-7,inhibit,GSK F1,PI4 kinases,PI3K
CBNumber
CB03067552
Molecular Formula
C27H18F5N5O4S
Formula Weight
603.52
MOL File
1402345-92-9.mol
More
Less

GSK-F1 Property

Boiling point:
744.3±70.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C, sealed storage, away from moisture and light
solubility 
DMSO : 125 mg/mL (207.12 mM; Need ultrasonic)
form 
Solid
pka
5.66±0.50(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Adipogen Life Sciences
Product number
SYN-1220-M005
Product name
GSK-F1
Purity
≥95%
Packaging
5mg
Price
$270
Updated
2021/12/16
Adipogen Life Sciences
Product number
SYN-1220-M010
Product name
GSK-F1
Purity
≥95%
Packaging
10mg
Price
$421
Updated
2021/12/16
DC Chemicals
Product number
DC10064
Product name
GSK-F1
Purity
>98%
Packaging
10mg
Price
$300
Updated
2021/12/16
More
Less

GSK-F1 Chemical Properties,Usage,Production

Uses

GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research[1].

IC 50

PI4KA: 8.0 (pIC50); PI3KD: 6.4 (pIC50); PI4KB: 5.9 (pIC50); PI3KB: 5.9 (pIC50); PI3KG: 5.9 (pIC50); PI3KA: 5.8 (pIC50)

References

[1] Bojjireddy N, et al. Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels. J Biol Chem. 2014 Feb 28;289(9):6120-32. DOI:10.1074/jbc.M113.531426

GSK-F1 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

GSK-F1 Suppliers

China 30 United Kingdom 1 United States 3 Global 34
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9119
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
Advantage
58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Suzhou Chenrui Biotechnology Co. LTD
Tel
17625585511
Fax
qq：1580084073
Email
1580084073@qq.com
Country
China
ProdList
959
Advantage
58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15727060112
Email
yutianchun2007@126.com
Country
China
ProdList
9814
Advantage
58
Hangzhou Taorui Biotechnology Co., Ltd
Tel
4000-360-990 15268198094
Email
sales@torreybio.com
Country
China
ProdList
3804
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62220
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
5929
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
Advantage
58
Shanghai Fine Biotech Co.，Ltd
Tel
18221172427
Email
sale@fine-biotech.com
Country
China
ProdList
2772
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Adipogen Life Sciences
Tel
41-6192660-40
Email
info@adipogen.com
Country
China
ProdList
5293
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
33024
Advantage
60
Guangzhou Aoz Biotechnology Co., Ltd.
Tel
18022383332
Country
CHINA
ProdList
0
Advantage
58
Shenzhen Zuoke Biotechnology Co., Ltd.
Tel
13532174601
Country
CHINA
ProdList
109
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6207
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Proteintech China
Tel
--
Fax
--
Email
Proteintech-CN@ptglab.com
Country
CHINA
ProdList
6290
Advantage
58

1402345-92-9, GSK-F1Related Search:


  • GSK-F1
  • rac-GSK-F1
  • CS-2666
  • PI4KA inhibitor-F1
  • 3-Pyridinesulfonamide, 5-[2-amino-3,4-dihydro-4-oxo-3-[2-(trifluoromethyl)phenyl]-6-quinazolinyl]-N-(2,4-difluorophenyl)-2-methoxy-
  • 5-{2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]-3,4-dihydro-6-quinazolinyl}-N-(2,4-difluorophenyl)-2-methoxy-3-pyridinesulfonamide
  • hepatitis C virus,Phosphoinositide 3-kinase,Inhibitor,HEK293-AT1 cells,GSK-F-1,PI4K,Phosphatidylinositol 4 kinases,GSK-F1,HCV,GSKF1,COS-7,inhibit,GSK F1,PI4 kinases,PI3K
  • GSK-F1, 10 mM in DMSO
  • 5-[2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide
  • 1402345-92-9
  • C27H18F5N5O4S