UCM05
- Product Name
- UCM05
- CAS No.
- 1094451-90-7
- Chemical Name
- UCM05
- Synonyms
- UCM05;G 28UCM;UCM05(G 28UCM);Benzoic acid, 3,4,5-trihydroxy-, 1,1'-(1,3-naphthalenediyl) ester;3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate
- CBNumber
- CB03067587
- Molecular Formula
- C24H16O10
- Formula Weight
- 464.38
- MOL File
- 1094451-90-7.mol
UCM05 Property
- Boiling point:
- 895.1±65.0 °C(Predicted)
- Density
- 1.652±0.06 g/cm3(Predicted)
- solubility
- DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:40): 0.02 mg/ml
- form
- A crystalline solid
- pka
- 7.50±0.25(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 19090
- Product name
- UCM05
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 19090
- Product name
- UCM05
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 19090
- Product name
- UCM05
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $214
- Updated
- 2024/03/01
- Product number
- 5446
- Product name
- G28UCM
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $883
- Updated
- 2021/12/16
- Product number
- 5446
- Product name
- G28UCM
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $210
- Updated
- 2021/12/16
UCM05 Chemical Properties,Usage,Production
Uses
UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 μM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of HER2, Akt, and ERK1/2, and growth of established xenografts in vivo. UCM05 also blocks the GTP-binding site of the cell division protein FtsZ from Bacillus, preventing bacterial division.[Cayman Chemical]
Uses
G 28UCM is a fatty acid synthase inhibitor with anticancer activity, novel inhibitor of fatty acid synthase with anticancer activity.
storage
Store at -20°C