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3-(pyridin-3-yl)propiolic acid

Product Name
3-(pyridin-3-yl)propiolic acid
CAS No.
59608-01-4
Chemical Name
3-(pyridin-3-yl)propiolic acid
Synonyms
3-(3-Pyridyl)propiolic acid;3-(pyridin-3-yl)propiolic acid;3-(3-Pyridinyl)-2-propynoic acid;3-(pyridin-3-yl)prop-2-ynoic acid;2-Propynoic acid, 3-(3-pyridinyl)-
CBNumber
CB03083974
Molecular Formula
C8H5NO2
Formula Weight
147.13
MOL File
59608-01-4.mol
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3-(pyridin-3-yl)propiolic acid Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P995795
Product name
3-(Pyridin-3-yl)propiolicAcid
Packaging
10mg
Price
$40
Updated
2021/12/16
Activate Scientific
Product number
AS26427
Product name
3-(3-Pyridyl)propiolic Acid
Purity
96+%
Packaging
250mg
Price
$338
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0313364
Product name
3-(PYRIDIN-3-YL)PROP-2-YNOIC ACID
Purity
95.00%
Packaging
5MG
Price
$500.36
Updated
2021/12/16
Activate Scientific
Product number
AS26427
Product name
3-(3-Pyridyl)propiolic Acid
Purity
96+%
Packaging
1g
Price
$675
Updated
2021/12/16
Activate Scientific
Product number
AS26427
Product name
3-(3-Pyridyl)propiolic Acid
Purity
96+%
Packaging
5G
Price
$1542
Updated
2021/12/16
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3-(pyridin-3-yl)propiolic acid Chemical Properties,Usage,Production

Uses

3-(Pyridin-3-yl)propiolic Acid (cas# 59608-01-4) is a useful reagent for the regio- and diastereoselective preparation of β-selenovinyl sulfones.

Synthesis

2510-23-8

124-38-9

59608-01-4

General method: 3-ethynylpyridine (1.0 mmol) was added to a 10 mL Schlenk tube equipped with a magnetic stirrer to which HSi(OEt)2Me (5.0 mmol) and KOtBu (1.5 mmol) had been pre-filled. The Schlenk tube was evacuated and backfilled with CO2, and this process was repeated three times. After connecting the CO2 gas bladder, the reactor was transferred to a water bath at 40 °C. After the reaction mixture was reacted under stirring conditions for 2 h, it was diluted with water (30 mL) and extracted with dichloromethane (3 × 10 mL). The aqueous layer was acidified with 6 M HCl aqueous solution and then extracted with diethyl ether (5 x 20 mL). The organic extracts were combined, dried with anhydrous Na2SO4 and subsequently concentrated under vacuum to give pure 3-(pyridin-3-yl)propargyl acid (as compound 3a, yield: 98%).

References

[1] Science China Chemistry, 2018, vol. 61, # 4, p. 449 - 456

3-(pyridin-3-yl)propiolic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(pyridin-3-yl)propiolic acid Suppliers

China 23 Hungary 1 India 1 United Kingdom 1 United States 6 Global 32
Alchem Pharmtech,Inc.
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Aladdin Scientific
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Synthonix Inc
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SynQuest Laboratories, Inc.
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AstaTech, Inc
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ARENA CHEMICAL
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59608-01-4, 3-(pyridin-3-yl)propiolic acidRelated Search:


  • 3-(pyridin-3-yl)propiolic acid
  • 3-(pyridin-3-yl)prop-2-ynoic acid
  • 3-(3-Pyridyl)propiolic acid
  • 2-Propynoic acid, 3-(3-pyridinyl)-
  • 3-(3-Pyridinyl)-2-propynoic acid
  • 59608-01-4