Proteasome Inhibitor XVI
- Product Name
- Proteasome Inhibitor XVI
- CAS No.
- 389064-25-9
- Chemical Name
- Proteasome Inhibitor XVI
- Synonyms
- Proteasome Inhibitor XVI;AdaAhxLVS - CAS 389064-25-9 - Calbiochem;L-Leucinamide, N-[1-oxo-6-[[1-oxo-6-[[1-oxo-6-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]hexyl]amino]hexyl]amino]hexyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]-
- CBNumber
- CB03121496
- Molecular Formula
- C50H88N6O8S
- Formula Weight
- 933.33
- MOL File
- 389064-25-9.mol
More
Less
Proteasome Inhibitor XVI Property
- Boiling point:
- 1161.4±65.0 °C(Predicted)
- Density
- 1.096±0.06 g/cm3(Predicted)
- storage temp.
- -20C
- form
- Off-white powder
- pka
- 13.41±0.46(Predicted)
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 114802
- Product name
- AdaAhx₃L₃VS - CAS 389064-25-9 - Calbiochem
- Purity
- A potent, covalent, cell-permeable, irreversible inhibitor of chymotrypsin-like (50-100 nM), trypsin-like (1-5 μM), and PGPH (0.5-1 μM) activities of the 20S proteasome.
- Packaging
- 250μg
- Price
- $390
- Updated
- 2024/03/01
More
Less
Proteasome Inhibitor XVI Chemical Properties,Usage,Production
General Description
A cell-permeable, peptide vinyl sulfone that acts as a potent, irreversible inhibitor of proteasome activity. Covalently modifies the catalytically active β-subunits of the proteasome. Shown to inhibit the chymotrypsin-like (10-50 nM), trypsin-like (1-5 μM), and the peptidyl glutamyl peptide hydrolyzing (PGPH) (0.5-1 μM) activities of purified 20S proteasomes from rabbit muscle. Inhibits proteasomal degradation of deglycosylated MHC HLA-A2 heavy chain in US11+ cells (~50 μM).
Biochem/physiol Actions
Cell permeable: yes
Proteasome Inhibitor XVI Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Proteasome Inhibitor XVI Suppliers
- Tel
- 0512-58900862 400-0707518
- Fax
- 0086-512-56765862
- sales@alabiochem.com
- Country
- China
- ProdList
- 995
- Advantage
- 59
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51471
- Advantage
- 80
- Tel
- 001-619-354-5251
- Fax
- 001-855-855-6087
- sales@alabiotech-e.com
- Country
- United States
- ProdList
- 972
- Advantage
- 60
- Tel
- +86-15542445688
- Fax
- 0086-411-39042693
- sales@alabiochem.com
- Country
- China
- ProdList
- 888
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19915
- Advantage
- 58