Cadazolid

Product Name: Cadazolid
CAS No.: 1025097-10-2
Chemical Name: Cadazolid
Synonyms: CS-2475;ACT179811;Cadazolid;ACT-179811;ACT 179811;Cadazolid (ACT-179811);Cadazolid, 10 mM in DMSO;Testosterone Impurity 44;ACT-179811; ACT 179811; ACT179811; CADAZOLID.;Cadazolid,Antibiotic,inhibit,ACT179811,Bacterial,Inhibitor,ACT 179811
CBNumber: CB03133943
Molecular Formula: C29H29F2N3O8
Formula Weight: 585.55
MOL File: 1025097-10-2.mol

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Cadazolid Property

Boiling point:: 832.6±65.0 °C(Predicted)
Density: 1.539±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:100.0(Max Conc. mg/mL);170.78(Max Conc. mM)
form: A crystalline solid
pka: 6.44±0.41(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23030
Product name: Cadazolid
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 23030
Product name: Cadazolid
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 23030
Product name: Cadazolid
Purity: ≥98%
Packaging: 10mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 23030
Product name: Cadazolid
Purity: ≥98%
Packaging: 25mg
Price: $533
Updated: 2024/03/01

ChemScene

Product number: CS-6972
Product name: Cadazolid
Purity: 97.44%
Packaging: 50mg
Price: $450
Updated: 2021/12/16

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Cadazolid Chemical Properties,Usage,Production

Uses

Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile.

in vivo

Cadazolid is well tolerated up to 3000 mg given twice daily for 10 days. The most common adverse event is headache, with no observed relationship between dose or treatment duration and adverse events. Plasma concentrations of cadazolid are low. No plasma concentrations >3.3 ng/mL are observed after single doses or >6.9 ng/mL after 10 days of multiple doses. Food increased the mean Cmax from 0.73 to 1.87 ng/mL and mean AUC0–t from 3.13 to 15.69 ng·h/mL after a single 300 mg dose. The increase in systemic exposure to cadazolid across doses is less than dose-proportional. The mean cumulative faecal recovery is 81.0%–93.5%. Urinary recovery of unchanged compound is less than 0.015%^[1].

IC 50

Oxazolidinone

References

[1] Baldoni D, et al. Cadazolid, a novel antibiotic with potent activity against Clostridium difficile: safety, tolerability and pharmacokinetics in healthy subjects following single and multiple oral doses. J Antimicrob Chemother. 2014 Mar;69(3):706-14. DOI:10.1093/jac/dkt401
[2] Chilton CH, et al. In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection. J Antimicrob Chemother. 2014 Mar;69(3):697-705. DOI:10.1093/jac/dkt411

Cadazolid Preparation Products And Raw materials

Raw materials

Preparation Products

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Cadazolid Suppliers

China 50 India 4 United States 7 USA 1 Global 62

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4768
Advantage: 55

Shanghai Beckham Medical Technology Co., Ltd

Tel: 13816613772
Fax: QQ: 12922499
Email: huahero21@sina.com
Country: China
ProdList: 2391
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1944
Advantage: 55

Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
Country: China
ProdList: 1991
Advantage: 58

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View Lastest Price from Cadazolid manufacturers

Career Henan Chemical Co

Product: Cadazolid 1025097-10-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-26

1025097-10-2, CadazolidRelated Search:

Torezolid

Cadazolid

ACT 179811

ACT179811

ACT-179811

ACT-179811; ACT 179811; ACT179811; CADAZOLID.

Cadazolid (ACT-179811)

CS-2475

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-7-[4-[[2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-3-oxazolidinyl]phenoxy]methyl]-4-hydroxy-1-piperidinyl]-1,4-dihydro-4-oxo-

Cadazolid,Antibiotic,inhibit,ACT179811,Bacterial,Inhibitor,ACT 179811

Testosterone Impurity 44

Cadazolid, 10 mM in DMSO

1025097-10-2

C29H29F2N3O8

API