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Cdk/Crk Inhibitor

Product Name
Cdk/Crk Inhibitor
CAS No.
784211-09-2
Chemical Name
Cdk/Crk Inhibitor
Synonyms
RGB-286147;Cdk/Crk Inhibitor;RGB 286147,RGB286147;Cdk/Crk Inhibitor - CAS 784211-09-2 - Calbiochem[219491];4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1-(2,6-dichlorophenyl)-1,5-dihydro-6-[[4-(2-hydroxyethoxy)phenyl]methyl]-3-(1-methylethyl)-
CBNumber
CB03136782
Molecular Formula
C23H22Cl2N4O3
Formula Weight
473.35
MOL File
784211-09-2.mol
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Cdk/Crk Inhibitor Property

Boiling point:
677.0±65.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml
form 
White powder solid.
pka
14.23±0.10(Predicted)
color 
White to off-white
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Safety

WGK Germany 
WGK 1
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21195
Product name
CDK/CRK Inhibitor
Purity
≥98%
Packaging
1mg
Price
$184
Updated
2024/03/01
Cayman Chemical
Product number
21195
Product name
CDK/CRK Inhibitor
Purity
≥98%
Packaging
5mg
Price
$638
Updated
2024/03/01
TRC
Product number
C228133
Product name
CDK/CRKInhibitor
Packaging
1mg
Price
$160
Updated
2021/12/16
TRC
Product number
C228133
Product name
CDK/CRKInhibitor
Packaging
2.5mg
Price
$315
Updated
2021/12/16
AK Scientific
Product number
1618EM
Product name
Cdk/CrkInhibitor
Packaging
1mg
Price
$302
Updated
2021/12/16
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Cdk/Crk Inhibitor Chemical Properties,Usage,Production

Uses

Cdk/Crk Inhibitor is a pyrazolo-pyrimidinone compound that acts as a potent, selective & ATP-competitive inhibitor of Cdks.

Biological Activity

Cell permeable: yes', 'Primary Target
Cdk1/B, Cdk2/E, Cdk3/E, Cdk5/p35, Cdk7/H/MAT1, and Cdk9', 'Product competes with ATP.', 'Reversible: no', 'Target IC50: 48 nM, 15 nM, 9 nM, 10 nM, 71 nM, and 9 nM for Cdk1/B, Cdk2/E, Cdk3/E, Cdk5/p35, Cdk7/H/MAT1, and Cdk9, respectively

IC 50

CDK1/cyclinB: 48 nM (IC50); CDK2/E: 15 nM (IC50); CDK4/D1: 839 nM (IC50); cdk6/cyclin D3: 232 nM (IC50)

Cdk/Crk Inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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Cdk/Crk Inhibitor Suppliers

China 15 United States 7 Global 22
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7982
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29431
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58

784211-09-2, Cdk/Crk InhibitorRelated Search:


  • Cdk/Crk Inhibitor
  • RGB-286147
  • RGB 286147,RGB286147
  • 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1-(2,6-dichlorophenyl)-1,5-dihydro-6-[[4-(2-hydroxyethoxy)phenyl]methyl]-3-(1-methylethyl)-
  • Cdk/Crk Inhibitor - CAS 784211-09-2 - Calbiochem[219491]
  • 784211-09-2