ChemicalBook > CAS DataBase List > DM1-Sme

DM1-Sme

Product Name
DM1-Sme
CAS No.
138148-68-2
Chemical Name
DM1-Sme
Synonyms
DM1-Sme;CS-2715;DM1-SSMe;AP3 Intermidate 2;MaytansinoidDM4Impurity6;1H-Inden-2-ol,1-amino-2,3-dihydro-,(1R,4S)-;N2'-Deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine;Maytansine, N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]-;4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1 10,14.03,5]hexacosane,maytansine deriv.;maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative
CBNumber
CB03139071
Molecular Formula
C36H50ClN3O10S2
Formula Weight
784.38
MOL File
138148-68-2.mol
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DM1-Sme Property

Boiling point:
957.1±65.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:12.0(Max Conc. mg/mL);15.3(Max Conc. mM)
DMF:16.0(Max Conc. mg/mL);20.4(Max Conc. mM)
DMF:PBS (pH 7.2) (1:5):0.16(Max Conc. mg/mL);0.2(Max Conc. mM)
form 
A crystalline solid
pka
9.82±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H303May be harmfulif swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22477
Product name
DM1-SMe
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
22477
Product name
DM1-SMe
Purity
≥98%
Packaging
5mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
22477
Product name
DM1-SMe
Purity
≥98%
Packaging
10mg
Price
$299
Updated
2024/03/01
Cayman Chemical
Product number
22477
Product name
DM1-SMe
Purity
≥98%
Packaging
25mg
Price
$638
Updated
2024/03/01
DC Chemicals
Product number
DC11396
Product name
DM1-SMe
Purity
>98%
Packaging
100mg
Price
$750
Updated
2021/12/16

DM1-Sme Preparation Products And Raw materials

Raw materials

Preparation Products

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DM1-Sme Suppliers

China 47 United States 7 Global 54
Hefei Hirisun Pharmatech Co., Ltd.
Tel
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Nova(Shanghai) Pharmaceutical Co.,Ltd
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DC Chemicals
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138148-68-2, DM1-SmeRelated Search:


  • DM1-Sme
  • N2'-Deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine
  • AP3 Intermidate 2
  • CS-2715
  • DM1-SME; DM1-SSME; MAYTANSINOID DERIVATIVE WITH ADC LINKER. MAYTANSINE OR MERTANSINE OR EMTANSINE DERIVATIVE; N2'-DEACETYL-N2'-[3-(METHYLDITHIO)-1-OXOPROPYL]MAYTANSINE.
  • DM1-SSMe
  • maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative
  • Maytansine, N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]-
  • 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1 10,14.03,5]hexacosane,maytansine deriv.
  • (14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-Chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methyldisulfaneyl)propanoyl)-L-alaninate
  • MaytansinoidDM4Impurity6
  • 1H-Inden-2-ol,1-amino-2,3-dihydro-,(1R,4S)-
  • Microtubule/Tubulin,ADC Payload,anti-tumor activity,tumor cell,DM1 SMe,DM1-SMe,inhibit,Inhibitor,maytansinoid,ADC Cytotoxin,DM-1-SMe,antibody-drug conjugate,DM1SMe
  • 138148-68-2
  • C36H50ClN3O10S2