ChemicalBook > CAS DataBase List > (2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

Product Name
(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
CAS No.
1422361-25-8
Chemical Name
(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
Synonyms
Emtricitabine Impurity 21;5-Fluoro-1-(2’-L-menthyloxycarbonyl-1’-3’-oxathiolan-5’-yl)-cytosine;(1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabine Uracil Carboxylate;(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester;1,3-Oxathiolane-2-carboxylic acid, 5-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2R,5S)-
CBNumber
CB03139657
Molecular Formula
C18H25FN2O5S
Formula Weight
400.46
MOL File
1422361-25-8.mol
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(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Property

Density 
1.32±0.1 g/cm3(Predicted)
pka
7.51±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
I779120
Product name
(1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabineUracilCarboxylate
Packaging
10mg
Price
$525
Updated
2021/12/16
Biosynth Carbosynth
Product number
NF58425
Product name
5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine
Packaging
500mg
Price
$825
Updated
2021/12/16
Biosynth Carbosynth
Product number
NF58425
Product name
5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine
Packaging
1g
Price
$1430
Updated
2021/12/16
Biosynth Carbosynth
Product number
NF58425
Product name
5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine
Packaging
50mg
Price
$90.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
NF58425
Product name
5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine
Packaging
100mg
Price
$145
Updated
2021/12/16
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(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Chemical Properties,Usage,Production

Uses

(1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabine Uracil Carboxylate is the uracil impurity of the parent compound Emtricitabine, E525000, which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).

(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester Suppliers

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1422361-25-8, (2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl esterRelated Search:


  • (2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
  • Emtricitabine Impurity 21
  • (1S,2R,4R)-1-Isopropyl-2,4-dimethylcyclohexyl-emtricitabine Uracil Carboxylate
  • 5-Fluoro-1-(2’-L-menthyloxycarbonyl-1’-3’-oxathiolan-5’-yl)-cytosine
  • 1,3-Oxathiolane-2-carboxylic acid, 5-(5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2R,5S)-
  • 1422361-25-8