ChemicalBook > CAS DataBase List > 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

Product Name
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
CAS No.
740081-22-5
Chemical Name
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
Synonyms
6-acetoxy-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline;4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl ...;4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate;6-Quinazolinol, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate
CBNumber
CB03145935
Molecular Formula
C17H13ClFN3O3
Formula Weight
361.75
MOL File
740081-22-5.mol
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4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Property

Boiling point:
454.4±45.0 °C(Predicted)
Density 
1.425±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
5.22±0.30(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C989238
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylAcetate
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
5764DN
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Packaging
1g
Price
$92
Updated
2021/12/16
Chemenu
Product number
CM216563
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Purity
97%
Packaging
5g
Price
$184
Updated
2021/12/16
Alichem
Product number
740081225
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Packaging
5g
Price
$189
Updated
2021/12/16
Ambeed
Product number
A143974
Product name
4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ylacetate
Purity
97%
Packaging
25g
Price
$223
Updated
2021/12/16
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4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Chemical Properties,Usage,Production

Description

AZD3759 is a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) on the basis of gefitinib and has been proven to enter the central nervous system. Although the promising antitumor effects of AZD3759 on non-small cell lung cancer (NSCLC) have been demonstrated in clinical trials, the regulatory effects of this inhibitor on the antitumor efficacy of radiation (RA) are unclear. AZD3759 Intermediate 2 is a key intermediate in the synthesis of AZD3759.

Uses

AZD3759 Intermediate 2 can be used as a pharmaceutical intermediate.

4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate Suppliers

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View Lastest Price from 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate manufacturers

Shanghai Rlavie Technology Co ltd
Product
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate 740081-22-5
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
25kgs/month
Release date
2021-11-18
Career Henan Chemical Co
Product
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate 740081-22-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-17

740081-22-5, 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetateRelated Search:


  • 6-acetoxy-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline
  • 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate
  • 6-Quinazolinol, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate
  • 4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl ...
  • 740081-22-5