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CP 94253 hydrochloride

Product Name
CP 94253 hydrochloride
CAS No.
845861-39-4
Chemical Name
CP 94253 hydrochloride
Synonyms
CP 94253 dihydrochloride, 5-HT1B agonist;1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-,monohydrochloride;CP94253,CP94253 hydrochloride,Serotonin Receptor,inhibit,CP 94253,CP-94253,5-hydroxytryptamine Receptor,Inhibitor,5-HT Receptor
CBNumber
CB03146275
Molecular Formula
C15H20ClN3O
Formula Weight
293.8
MOL File
845861-39-4.mol
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CP 94253 hydrochloride Property

storage temp. 
Desiccate at RT
solubility 
Soluble to 25 mM in water and to 100 mM in DMSO
form 
Powder
color 
Pale yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29486
Product name
CP 94,253 (hydrochloride)
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
29486
Product name
CP 94,253 (hydrochloride)
Packaging
25mg
Price
$336
Updated
2024/03/01
Cayman Chemical
Product number
29486
Product name
CP 94,253 (hydrochloride)
Packaging
10mg
Price
$152
Updated
2024/03/01
TRC
Product number
P398983
Product name
CP94253Hydrochloride
Packaging
5mg
Price
$210
Updated
2021/12/16
ApexBio Technology
Product number
B6685
Product name
CP94253hydrochloride
Packaging
10mg
Price
$308
Updated
2021/12/16
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CP 94253 hydrochloride Chemical Properties,Usage,Production

Description

CP 94,253 is an agonist of the serotonin (5-HT) receptor subtype 5-HT1B (Ki = 2 nM in a radioligand binding assay). It is selective for 5-HT1B over 5-HT1A, 5-HT1D, 5-HT1C, and 5-HT2 receptors (Kis = 89, 49, 860, and 1,600 nM, respectively). CP 94,253 (10 and 17 mg/kg) reduces aggressive behavior in a resident-intruder test in mice, as well as decreases alcohol-induced aggression in mice with an ED50 value of 3.8 mg/kg. It decreases the time mice spend immobile in the forced swim test by 43%, indicating antidepressant-like activity, when administered at a dose of 5 mg/kg. CP 94,253 (2.5 mg/kg) also increases drinking in the Vogel punished drinking task, indicating anxiolytic-like activity, in rats.

Uses

CP 94253 Hydrochloride is a potent and selective serotonin 5-HT1B receptor agonist with anticonvulsant activity.

storage

Desiccate at RT

CP 94253 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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CP 94253 hydrochloride Suppliers

China 23 United Kingdom 1 United States 5 USA 1 Global 30
Anqing YanZhi Pharma Discovery Co.,Ltd.
Tel
18055651951
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2272561977@qq.com
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China
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Finetech Industry Limited
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027-87465837 19945049750
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027-8777-2287
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Shanghai Lollane Biological Technology Co.,Ltd.
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021-52996696，15000506266 15000506266
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+86-21-52996696
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China
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ATK CHEMICAL COMPANY LIMITED
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021-51619050 13301662590
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+86-21-51619052
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mandy@atkchemical.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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China
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Chuzhou KeMail Chemical Technology Co., Ltd
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0550-5196001 15000891977
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0550-5196001
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Finetech Industry Limited
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Zhejiang J&C Biological Technology Co.,Limited
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+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
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China
ProdList
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DC Chemicals
Tel
021-58447131 13564518121
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sales@dcchemicals.com
Country
China
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ShenZhen Davoos Tech Ltd
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Chunchuang (Wuhan) Technology Co., Ltd
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Changzhou Furuisi Biotechnology Co., Ltd
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Bide Pharmatech Ltd.
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product02@bidepharm.com
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Wuhan Shanhai Zhihe Biotechnology Co., Ltd.
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TargetMol Chemicals Inc.
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marketing@tsbiochem.com
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Nantong QuanYi Biotechnology Co., Ltd
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sales@chemhifuture.com
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Nanjing Tengyi Biotechnology Co., Ltd
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https://hanhongsci.com/
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China
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Shanghai Mawei Biological Technology Co., LTD
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China
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ATK CHEMICAL COMPANY LIMITED
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Shanghai Maiev Biotech Co.,Ltd
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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845861-39-4, CP 94253 hydrochlorideRelated Search:


  • 1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-,monohydrochloride
  • CP94253,CP94253 hydrochloride,Serotonin Receptor,inhibit,CP 94253,CP-94253,5-hydroxytryptamine Receptor,Inhibitor,5-HT Receptor
  • CP 94253 dihydrochloride, 5-HT1B agonist
  • 845861-39-4