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Se-Aspirin

Product Name
Se-Aspirin
CAS No.
1850293-95-6
Chemical Name
Se-Aspirin
Synonyms
Se-Aspirin;2-((2-Selenocyanatoethyl)carbamoyl)phenyl acetate;Selenocyanic acid, 2-[[2-(acetyloxy)benzoyl]amino]ethyl ester
CBNumber
CB03152740
Molecular Formula
C12H12N2O3Se
Formula Weight
311.2
MOL File
1850293-95-6.mol
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Se-Aspirin Property

storage temp. 
Store at -20°C
solubility 
≤10mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
form 
crystalline solid
pka
13.48±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19315
Product name
Se-Aspirin
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
19315
Product name
Se-Aspirin
Purity
≥98%
Packaging
5mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
19315
Product name
Se-Aspirin
Purity
≥98%
Packaging
10mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
19315
Product name
Se-Aspirin
Purity
≥98%
Packaging
50mg
Price
$987
Updated
2024/03/01
ApexBio Technology
Product number
C5667
Product name
Se-Aspirin
Packaging
10mg
Price
$277
Updated
2021/12/16
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Se-Aspirin Chemical Properties,Usage,Production

Description

Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 μM). It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage. Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.

Uses

Se-Aspirin is a hybrid of selenium and a nonsteroidal anti-inflammatory drug that has been shown to reduce the viability of different cancer cell lines, particularly colorectal cancer (CRC) cells (IC50 = 3.4 μM). It can inhibit the cell cycle in G1 and G2/M phases and induce apoptosis by activating caspase 3/7 and PARP cleavage. Long-term exposure to Se-Aspirin is reported to cause an increase in intracellular reactive oxygen species levels in CRC cells.[Cayman Chemical]

References

[1] plano d, karelia d n, pandey m k, et al. design, synthesis, and biological evaluation of novel selenium (se-nsaid) molecules as anticancer agents[j]. journal of medicinal chemistry, 2016, 59(5): 1946-1959.

Se-Aspirin Preparation Products And Raw materials

Raw materials

Preparation Products

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Se-Aspirin Suppliers

China 10 United States 3 Global 13
Zhengzhou Huiju Chemical Co., Ltd.
Tel
0371-55900031 18137872243
Fax
QQ：2853979815
Email
2853979815@qq.com
Country
China
ProdList
9988
Advantage
55
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19699
Advantage
58
Neobioscience Co., Ltd.
Tel
--
Fax
--
Email
info@neobioscience.com
Country
CHINA
ProdList
6682
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6705
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Beijing Luyuan Bird Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
15810802415@139.com
Country
CHINA
ProdList
6750
Advantage
58
Boao Pike
Tel
--
Fax
--
Email
lyn@biopike.com.cn
Country
CHINA
ProdList
6629
Advantage
58
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58

1850293-95-6, Se-AspirinRelated Search:


  • Se-Aspirin
  • Selenocyanic acid, 2-[[2-(acetyloxy)benzoyl]amino]ethyl ester
  • 2-((2-Selenocyanatoethyl)carbamoyl)phenyl acetate
  • 1850293-95-6
  • C12H12N2O3Se