Boc-Aminooxy-PEG2-Azide
- Product Name
- Boc-Aminooxy-PEG2-Azide
- CAS No.
- 252378-68-0
- Chemical Name
- Boc-Aminooxy-PEG2-Azide
- Synonyms
- Boc-NH-O-PEG3-N3;Boc-Aminooxy-PEG2-Azide;t-Boc-Aminooxy-PEG2-azide;t-Boc-Aminooxy-PEG2-azide boc
- CBNumber
- CB03162899
- Molecular Formula
- C11H22N4O5
- Formula Weight
- 290.31618
- MOL File
- 252378-68-0.mol
Boc-Aminooxy-PEG2-Azide Property
- storage temp.
- Storage temp. 2-8°C
- form
- Viscous Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-22994
- Product name
- t-Boc-Aminooxy-PEG2-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- BP-22994
- Product name
- t-Boc-Aminooxy-PEG2-azide
- Purity
- 98%
- Packaging
- 1g
- Price
- $1400
- Updated
- 2021/12/16
Boc-Aminooxy-PEG2-Azide Chemical Properties,Usage,Production
Description
t-Boc-Aminooxy-PEG2-azide is a click chemistry crosslinker molecule. The azide group enables PEGylation via Click Chemistry. The protected aminooxy can be deprotected under acidic conditions and then can react with an aldehyde or ketone group to form a stable oxime linkage.
Uses
t-Boc-Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. t-Boc-Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Boc-Aminooxy-PEG2-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Boc-Aminooxy-PEG2-Azide manufacturers
- Product
- t-Boc-Aminooxy-PEG2-azide 252378-68-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-22