ChemicalBook > CAS DataBase List > AAD-2004
AAD-2004
- Product Name
- AAD-2004
- CAS No.
- 927685-43-6
- Chemical Name
- AAD-2004
- Synonyms
- AAD-2004;Crisdesalazine;Crisdesalazine (AAD-2004;Benzoic acid, 2-hydroxy-5-[[2-[4-(trifluoromethyl)phenyl]ethyl]amino]-
- CBNumber
- CB03168442
- Molecular Formula
- C16H14F3NO3
- Formula Weight
- 325.28
- MOL File
- 927685-43-6.mol
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AAD-2004 Property
- Melting point:
- >300 °C
- Boiling point:
- 496.4±45.0 °C(Predicted)
- Density
- 1.410±0.06 g/cm3(Predicted)
- pka
- 2.31±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
Crysdot
- Product number
- CD12005808
- Product name
- 2-Hydroxy-5-((4-(trifluoromethyl)phenethyl)amino)benzoicacid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $396
- Updated
- 2021/12/16
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AAD-2004 Chemical Properties,Usage,Production
Uses
Crisdesalazine (AAD-2004) is an anti-inflammatory agent that simultaneously blocks inflammation mediated by free radicals and prostaglandin E2 (PGE2). Crisdesalazine (AAD-2004) can be used to study neurodegeneration in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases[1].
References
[1] Shin JH, et al. Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis. J Neurochem. 2012 Sep;122(5):952-61. DOI:10.1111/j.1471-4159.2012.07771.x
AAD-2004 Preparation Products And Raw materials
Raw materials
Preparation Products
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