Adenosine, 2-chloro-N-methyl-

Product Name: Adenosine, 2-chloro-N-methyl-
CAS No.: 13406-50-3
Chemical Name: Adenosine, 2-chloro-N-methyl-
Synonyms: Regadenoson Impurity 43;2-Chloro-N6-methyladenosine;Adenosine, 2-chloro-N-methyl-;(2R,3R,4S,5R)-2-(2-hydrazinyl-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;(2R,3R,4S,5R)-2-(2-Chloro-6-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CBNumber: CB03185038
Molecular Formula: C11H14ClN5O4
Formula Weight: 315.71
MOL File: 13406-50-3.mol

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Adenosine, 2-chloro-N-methyl- Property

Boiling point:: 623.5±65.0 °C(Predicted)
Density: 1.96±0.1 g/cm3(Predicted)
pka: 13.06±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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Adenosine, 2-chloro-N-methyl- Chemical Properties,Usage,Production

Uses

2-Chloro-N6-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

Adenosine, 2-chloro-N-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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Adenosine, 2-chloro-N-methyl- Suppliers

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13406-50-3, Adenosine, 2-chloro-N-methyl-Related Search:

Regadenoson Impurity 10 Regadenoson Impurity 3 Guanosine, hydrazone Regadenoson Impurity 57 9H-Purin-6-amine, 9-b-D-arabinofuranosyl-2-chloro- Regadenoson Impurity 5 Methyl 2-forMyl-3,3-diMethoxypropanoate Xanthosine, dioxime(9CI) Adenosine, N-methyl-2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]- Regadenoson Impurity 1 NSC 36898 1H-Pyrazole-4-carboxamide, 1-(6-amino-9H-purin-2-yl)-N-methyl- SODIUM (E)-2-(DIMETHOXYMETHYL)-3-METHOXY-3-OXOPROP-1-EN-1-OLATE 2-Propenoic acid, 2-(dimethoxymethyl)-3-hydroxy-, methyl ester CVT 3127 sodium(Z)-2-(dimethoxymethyl)-3-methoxy-3-oxoprop-1-en-1-olate 9H-Purin-2-amine, 9-β-D-arabinofuranosyl-6-chloro- 2-[4-[(ethylamino)carbonyl]-1H-pyrazol-1-yl]adenosine

Adenosine, 2-chloro-N-methyl-

2-Chloro-N6-methyladenosine

(2R,3R,4S,5R)-2-(2-Chloro-6-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Regadenoson Impurity 43

(2R,3R,4S,5R)-2-(2-hydrazinyl-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

13406-50-3