ChemicalBook > CAS DataBase List > Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-

Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-

Product Name
Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
CAS No.
52485-51-5
Chemical Name
Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
Synonyms
N-Acetyl-L-phenylalaninol;(S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide;Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
CBNumber
CB03222876
Molecular Formula
C11H15NO2
Formula Weight
193.24
MOL File
52485-51-5.mol
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Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Property

storage temp. 
Sealed in dry,Room Temperature
Appearance
White to off-white Solid
optical activity
Consistent with structure
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
8555CS
Product name
(S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
Packaging
100mg
Price
$165
Updated
2021/12/16
AK Scientific
Product number
8555CS
Product name
(S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
Packaging
1g
Price
$465
Updated
2021/12/16
aablocks
Product number
AA01EMYM
Product name
(S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
Purity
97%
Packaging
100mg
Price
$103
Updated
2021/12/16
Crysdot
Product number
CD12065183
Product name
(S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
Purity
97%
Packaging
100mg
Price
$117
Updated
2021/12/16
aablocks
Product number
AA01EMYM
Product name
(S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
Purity
97%
Packaging
250mg
Price
$152
Updated
2021/12/16
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Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Chemical Properties,Usage,Production

Synthesis

3182-95-4

108-24-7

52485-51-5

General procedure for the synthesis of (S)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide from L-phenylalaninol and ethanoic anhydride: L-phenylalaninol (1 mmol) was mixed with ethanoic anhydride (1.2 mmol) in a 50 mL round-bottomed flask and the reaction was stirred at room temperature until complete (monitored by TLC). After completion of the reaction, the mixture was dissolved in ether (5 mL) and allowed to stand at room temperature for 1 hour. During this time, the product (S)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide precipitated as crystals, which were collected by filtration. For the reaction of solid substrates (e.g., sulfonamides), the same operating procedure is used, but the solubility of the mixture is adjusted with water.The N-acylated sulfonamide product is obtained by crystallization from diethyl ether.

References

[1] Chinese Chemical Letters, 2010, vol. 21, # 2, p. 155 - 158
[2] Oriental Journal of Chemistry, 2015, vol. 31, # 2, p. 913 - 919
[3] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 10, p. 2742 - 2755
[4] Patent: US6750348, 2004, B1. Location in patent: Page column 47
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 6, p. 2216 - 2220

Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Suppliers

BOC Sciences
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United States
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Bide Pharmatech Ltd.
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China
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Amadis Chemical Company Limited
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Energy Chemical
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52485-51-5, Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-Related Search:


  • Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
  • (S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
  • N-Acetyl-L-phenylalaninol
  • 52485-51-5