Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
- Product Name
- Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
- CAS No.
- 52485-51-5
- Chemical Name
- Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
- Synonyms
- N-Acetyl-L-phenylalaninol;(S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide;Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
- CBNumber
- CB03222876
- Molecular Formula
- C11H15NO2
- Formula Weight
- 193.24
- MOL File
- 52485-51-5.mol
Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
- optical activity
- Consistent with structure
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8555CS
- Product name
- (S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
- Packaging
- 100mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 8555CS
- Product name
- (S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
- Packaging
- 1g
- Price
- $465
- Updated
- 2021/12/16
- Product number
- AA01EMYM
- Product name
- (S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
- Purity
- 97%
- Packaging
- 100mg
- Price
- $103
- Updated
- 2021/12/16
- Product number
- CD12065183
- Product name
- (S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
- Purity
- 97%
- Packaging
- 100mg
- Price
- $117
- Updated
- 2021/12/16
- Product number
- AA01EMYM
- Product name
- (S)-N-(1-Hydroxy-3-phenylpropan-2-yl)acetamide
- Purity
- 97%
- Packaging
- 250mg
- Price
- $152
- Updated
- 2021/12/16
Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Chemical Properties,Usage,Production
Synthesis
3182-95-4
108-24-7
52485-51-5
General procedure for the synthesis of (S)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide from L-phenylalaninol and ethanoic anhydride: L-phenylalaninol (1 mmol) was mixed with ethanoic anhydride (1.2 mmol) in a 50 mL round-bottomed flask and the reaction was stirred at room temperature until complete (monitored by TLC). After completion of the reaction, the mixture was dissolved in ether (5 mL) and allowed to stand at room temperature for 1 hour. During this time, the product (S)-N-(1-hydroxy-3-phenylpropan-2-yl)acetamide precipitated as crystals, which were collected by filtration. For the reaction of solid substrates (e.g., sulfonamides), the same operating procedure is used, but the solubility of the mixture is adjusted with water.The N-acylated sulfonamide product is obtained by crystallization from diethyl ether.
References
[1] Chinese Chemical Letters, 2010, vol. 21, # 2, p. 155 - 158
[2] Oriental Journal of Chemistry, 2015, vol. 31, # 2, p. 913 - 919
[3] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 10, p. 2742 - 2755
[4] Patent: US6750348, 2004, B1. Location in patent: Page column 47
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 6, p. 2216 - 2220
Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
Acetamide, N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- Suppliers
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