LOXIGLUMIDE

ChemicalBook > CAS DataBase List > LOXIGLUMIDE

Product Name: LOXIGLUMIDE
CAS No.: 107097-80-3
Chemical Name: LOXIGLUMIDE
Synonyms: CS-162;cr1505;anoicacid;(+-)--5-oxo;LOXIGLUMIDE;ntanoicacid;Loxiglumide, >98%;LoxigluMide (CR1505);Loxiglumide >=97% (HPLC);Loxiglumide, 10 mM in DMSO
CBNumber: CB0326090
Molecular Formula: C21H30Cl2N2O5
Formula Weight: 461.38
MOL File: 107097-80-3.mol

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LOXIGLUMIDE Property

Melting point:: 113-115℃
Boiling point:: 632.2±55.0 °C(Predicted)
Density: 1.233±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥5mg/mL
pka: pKa ~5(at 25℃)
form: powder
color: white to beige
CAS DataBase Reference: 107097-80-3

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0130
Product name: Loxiglumide
Purity: ≥97% (HPLC)
Packaging: 10mg
Price: $96.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0130
Product name: Loxiglumide
Purity: ≥97% (HPLC)
Packaging: 50mg
Price: $313
Updated: 2024/03/01

Cayman Chemical

Product number: 25534
Product name: Loxiglumide
Purity: ≥98%
Packaging: 5mg
Price: $56
Updated: 2024/03/01

Cayman Chemical

Product number: 25534
Product name: Loxiglumide
Purity: ≥98%
Packaging: 10mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 25534
Product name: Loxiglumide
Purity: ≥98%
Packaging: 25mg
Price: $201
Updated: 2024/03/01

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LOXIGLUMIDE Chemical Properties,Usage,Production

Uses

Loxiglumide is a CCK1 antagonist. Suppresses CCK-induced proliferation of acinar cells. Inhibits pancreatic secretion of digestive enzymes. Active in vivo.

Definition

ChEBI: Loxiglumide is an organic molecular entity.

Biochem/physiol Actions

Loxiglumide is a small-molecule antagonist of the cholecystokinin receptor CCKA. Loxiglumide inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying.

Safety Profile

A poison by intravenous. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic vapors of NOx and Cl-.

storage

Store at -20°C

LOXIGLUMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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107097-80-3, LOXIGLUMIDERelated Search:

Transglutaminase PYRIDINE-2-CARBOXALDOXIME METHIODIDE 4-(4-CHLORO-BENZOYLAMINO)-BUTYRIC ACID N-(3-CHLOROBENZYL)BUTAN-1-AMINE Proglumide DL-GAMMA-ORNITHINE DIHYDROCHLORIDE LOXIGLUMIDE DEXLOXIGLUMIDE

4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid

4-[(3,4-dichlorophenyl)carbonylamino]-5-[3-methoxypropyl(pentyl)amino]-5-oxo-pentanoic acid

5-[amyl(3-methoxypropyl)amino]-4-[(3,4-dichlorobenzoyl)amino]-5-keto-valeric acid

LoxigluMide (CR1505)

LOXIGLUMIDE

CS-162

Loxiglumide, >98%

(+-)-4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)-5-oxope

(+-)--5-oxo

anoicacid

cr1505

d,l-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pent

ntanoicacid

pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)

Pentanoic acid, 4-[(3,4-dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxo-

Loxiglumide >=97% (HPLC)

CR1505,CR 1505,CCK Receptor,Inhibitor,Loxiglumide,inhibit,Cholecystokinin Receptor

4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoicacid

4-[(3,4-dichlorophenyl)formamido]-4-[(3-methoxypropyl)(pentyl)carbamoyl]butanoic acid

Loxiglumide, 10 mM in DMSO

107097-80-3

C21H30Cl2N2O5

Inhibitors